摘要

Objectives: This study aims to share the results of 1,500 exosome treatments administered to hair transplant and non-transplant individuals over one year. Exosomes play a crucial role in cell-to-cell components in regenerative medicine. Their application in scalp treatments has demonstrated promising results. This presentation highlights the importance of exosomes in improving treatment outcomes for androgenetic alopecia with overall patient satisfaction Introduction: Plant-derived exosomes are emerging as a safe and effective cell-free therapy for scalp regeneration. In this study, we selected the HRLV exosome formulation due to its RSCE (Root Stem Cell Extract) content, which is rich in miRNA-122-5p. This specific miRNA has been shown to counteract the effects of DHT on hair follicles by reducing inflammation and promoting follicular cell survival, making HRLV a promising option for androgenetic alopecia management. Materials / method: A total of 1,500 exosome treatments were conducted from September 2023 to March 2025 with Exocobio HRLV (RSCE) product in Doku Clinic. The study assessed the efficacy and short-term safety of these treatments, focusing on both patients who underwent hair transplantation and those who did not. Clinical outcomes were monitored through regular follow-ups and evaluations of hair growth, scalp health, and patient satisfaction with 3 month 6 months 1 year before after pictures. Results: Results from this extensive study will be discussed in detail, emphasizing the differences in treatment outcomes between individuals who received hair transplants and those who did not. Key metrics will include the rates of hair growth, scalp health improvement, and any reported adverse effects. Visual aids, including images, will be used to illustrate the results, and a thorough analysis of the proportionate outcomes will be elaborated upon during the presentation. Conclusion: The findings from this study will provide valuable insights into the safety and effectiveness of plant-based rose stem cell exosome treatments for androgenetic alopecia. This research has the potential to enhance current treatment protocols and improve patient outcomes in the field of hair restoration.