摘要

Objectives: To evaluate the combined use of EBD and topical Collagenase and Lipase to improve cellulite Introduction: Cellulite, also known as nodular liposclerosis is a complex disorder of skin's architecture that results in dimpling at surface level that is commonly known as orange peel. It has been reported that between 80 and 90% of women over 20 years of age suffer this condition. Radiofrequency (RF) devices or Energy-Based Equipment (EBD) are preferred over many traditional aesthetic methods. Use of lipolytic enzymes mixed with hyaluronidase and collagenase in dermatology has been applied topically with little evidence. No publications on cellulite are found. The aim of this stud Materials / method: A total of 20 women were studied and divided into two groups: a group of 10 was administered radiofrequency and the other had enzymes added, which were diluted in 5 cm3 of physiological saline and 2.5 cm3 were applied with the active plates. . placed on the thighs for 10 minutes and the rest with capacitive and resistive electrodes, massaging energetically for 10 more minutes. Ultrasound and measurement of the diameter of the treated area were performed Results: The energy-based device was applied is a reduction of 6.1 cm in diameter for the energy treatment alone, and when the application of energy is carried out in conjunction with enzymes the loss is 14.8 cm. The average of the three ultrasound measurements of thigh fat shows a difference of 8.77 mm after treatment with energy alone, while when combined with enzymes the loss is 14.64 mm. The ANOVA test gives a statistically significant difference p= 0.001. Conclusion: The combined use of the high-potency EBD with 4 channel and enzymes has been shown to be effective for the reduction of cellulite in women, decreasing the diameter of the treated area and the appearance of the skin. This research opens a new path in the treatment of this pathology, which makes patients so uncomfortable due to its aesthetic consequences.