摘要

Objectives: Genital aesthetics for both male and female has rapidly evolved from a niche offering to a recognized component of comprehensive aesthetic and sexual wellness care. With increasing patient demand, non surgical novel technologies including energy-based devices, injectable biostimulators, regenerative therapies (PRP, exosomes), and minimally invasive surgical techniques are reshaping practice. This abstract aims to review current techniques and the future role of biostimulators and radiofrequency procedures for erectile dysfunction and genital aesthetics. Introduction: Literature review of clinical studies and consensus statements (2018–2025). Comparative analysis of trends in Europe, Asia, and the United States. Evaluation of emerging therapies: polynucleotides, stem cell-derived exosomes, radiofrequency microneedling combinations. Patient-reported outcomes and safety profiles from multicenter data. In regards to Erectile dysfunction, RF has shown promise in tissue remodeling through neocollageneis and angiogenesis. Materials / method: Literature review of clinical studies and consensus statements (2018–2025). Comparative analysis of trends in Europe, Asia, and the United States. Evaluation of emerging therapies: polynucleotides, stem cell-derived exosomes, radiofrequency–microneedling combinations. Patient-reported outcomes and safety profiles from multicenter data. Results: Energy-based devices (laser, RF, HIFU) remain the cornerstone in non-surgical tightening and functional enhancement. Injectables (hyaluronic acid, CaHA, PRP, exosomes) show promise for vulvovaginal rejuvenation, hydration, and sensitivity improvement. Cultural differences shape demand: U.S. focuses on function and comfort, Europe emphasizes natural outcomes, while Asia/Korea embraces regenerative and stacked procedures. . Patient satisfaction is high when therapies address both aesthetic and functional needs. Conclusion: Genital aesthetics is emerging as a vital subspecialty that bridges functional medicine, sexual health, and aesthetic practice. The field is moving toward regenerative, combination-based protocols with high patient satisfaction. However, standardized training, evidence-based guidelines, and ethical clarity remain essential. Its integration into mainstream aesthetics reflects a paradigm shift from purely cosmetic procedures to holistic wellness. Further investigation into these therapies should be done in larger controlled trials.