摘要

Objectives: Obese elderly are also likely to have functional limitations because of the decreased muscle mass and strength, increased joint dysfunction, disabilities of activities of daily living, frailty, chronic pain, and impaired quality of life Obesity is characterized by a state of low-grade, chronic inflammation, marked by elevated circulating proinflammatory molecules produced predominantly by enlarged adipocytes and activated macrophages in adipose tissue. Sarcopenic obesity is defined as a gradual loss of muscle mass and functionality with an excess of adipose tissue (TA) in an aging population Introduction: Body movements are essential for maintaining stability. Skeletal muscle tissue accounts for nearly half of the human body's mass and, besides its role in power generation, plays a crucial role in maintaining homeostasis. Given its central role in human mobility and metabolic function, any deterioration in the contractile, structural, and metabolic properties of skeletal muscle has a profoundly significant impact on human health. Materials / method: Aging is associated with a progressive decline in muscle mass, quality, and strength, a condition known as sarcopenia. Another morphological aspect of sarcopenia is the infiltration of muscle tissue components by lipids. Obesity is associated with increased morbidity and mortality. Sarcopenic Obesity Aging is associated with substantial changes in body composition and metabolism Results: Variations during the menopausal transition can influence the amount and composition of adipose tissue mass. E2 affects numerous pathways of energy homeostasis. Women have a higher tendency to develop obesity and other metabolic syndromes. Dysregulation of leptin and kisspeptin signaling as anorectic agents Conclusion: Sarcopenic obesity is defined as a gradual loss of muscle mass and functionality with an excess of adipose tissue in an aging population. Therapeutic Application Physical Exercise. Nutrition and Diet. Novel nutritional strategies, including improvements in muscle mass, strength, fall prevention, and modulation of inflammation. The potential role of emerging nutritional supplements. Obesity, and specifically sarcopenic obesity, in the elderly is potentially preventable