摘要

Objectives: This study seeks to assess the efficacy and safety of PDLLA injections targeted atthe zygomatic ligament and to explore their potential impact on facial rejuvenation. Introduction: Currently, various polymers have been investigated for their ability to provide subtle, long-lasting rejuvenation effects. Among these, poly-D,L-lactic acid (PDLLA) has emerged as a promising option. While numerous studies have demonstrated the efficacy of PDLLA in skin rejuvenation, the treatment of stretchmarks, and the repair of acne scars, research focusing on its effects on facial ligaments remains limited Materials / method: A female patient with mild gravitational ptosis affecting bothcheeks due to aging underwent bilateral injections of PDLLA. Standardized clinical photographs and ultrasound images weretaken at baseline and at follow-up appointments to monitoroutcomes. All imaging was conducted under controlled lightingand patient positioning within a designated photography space. Posttreatment images were assessed separately by the physicianand the patient using the GAIS. Ultrasound examination conducted 3 weeks afterthe final treatment. Results: This study demonstrated noticeable improvements in ligament thickness and clinical outcomes following PDLLA injections. The unique rheological and biostimulatory properties of PDLLA, combined with precise placement beneath a lax zygomatic ligament, effectively addressed ligament laxity and stimulated neocollagenesis simultaneously. The procedure proved to be an effective intervention for correcting age-related changes in patients with mild to moderate gravitational ptosis.The patient reported high satisfaction, describing a lifting and supportive effect on her cheeks. Conclusion: this study provides compelling evidence that PDLLA injections can strengthen facial ligaments and deliver an indirect lifting effect on overlying tissues, offering a promis-ing approach to facial rejuvenation