摘要

Objectives: Patient care following botulinum toxin injections has long been guided by anecdotal instructions, often based on theoretical considerations. This study evaluates the necessity of extended post-treatment instructions by analyzing outcomes and satisfaction in patients who followed only a 10 min precaution protocol. Introduction: Botulinum toxin type A (BoNT-A) is widely used for facial rejuvenation, effectively reducing dynamic wrinkles with a well-established safety profile. Traditional post-treatment guidelines recommend activity restrictions for several hours, though these are largely anecdotal. Materials / method: A retrospective, multicentric study was conducted across six Italian centers, analyzing 5014 patients treated with botulinum toxin for upper facial wrinkles between 2015 and 2020. Outcomes included adverse effects—particularly upper eyelid ptosis—and patient satisfaction. Follow-up was performed at two weeks. Results: No cases of upper eyelid ptosis were observed. Among 4000 patients who attended follow-up, adverse effects occurred in only 5.99%, notably lower than rates reported in the literature. Of the 2010 patients who completed the satisfaction questionnaire, 90% reported being very satisfied. These findings support the safety of limiting post-treatment instructions to 10 min Conclusion: This study challenges several long-held beliefs about post-botulinum toxin care, suggesting that many traditional recommendations may not be necessary. As BoNT-A is rapidly internalized, the timeframe for potential complications is brief, and extended restrictions may be unnecessary.