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Objectives: Minoxidil, whose clear mechanism of action is still unknown, is administered mainly topically in concentrations of 2-5%. Finasteride plays a key role in the treatment of AGA in men and in post-menopausal women. Dutasteride is an anti-androgen like finasteride. As it blocks both type 1 and 2 of 5 α reductase, it seems to be more effective in AGA in both oral and topical use.

Introduction: Alopecia is the disease that consists of generalized or localized hair loss situated in the scalp or the body. The most common types are androgenetic alopecia (AGA), alopecia areata, diffuse alopecia and cicatricial alopecia.

Conclusion: New, very promising autologous treatments include Stem Cells, Exosomes, Regenera but more clinical evidence is needed to establish the extensive use of them. Other, less common treatments, include medications such as corticosteroids, JAK inhibitors, hydroxychloroquine in autoimmune causes of hair loss, spironolactone in female AGA and Low Level Laser Therapy devices in various types of alopecia. It is very important to underline that conservative treatments are more effective in combination as they have a multiplying effect and the effectiveness lasts for as long as the treatments are used.

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Objectives: The number of clinical trials evaluating new regenerative and innovative strategies in male and female pattern hair loss have exponentially increased during the last five years.Non surgical techniques in hair loss have shown qualitatively and quantitatively beneficial n the efficacy of oral and procedural combination therapy. Additional studies  are needed to further investigate and confirm the efficacy of combination therapies with establishing standardized measure of treatment success.

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