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Objectives: During my conference, I will show the different surgical and non-surgical techniques to improve facial fat deflation, especially in the middle third of the face.

Introduction: There are different causes and degrees of facial lipoatrophy that require different types of therapeutic approaches.

Materials / method: 26 years of experience performing facial improvements due to lipoatrophy using synthetic fillers, fat grafts and different types of prostheses

Results: They will be shown during my lecture

Conclusion: Depending on the cause and degree of facial lipoatrophy, depending on the surgical or non-surgical qualities of the medical doctor can be resolved by different therapeutic options.

利益冲突声明

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你是否拥有或者您已经为您此研究中的工具，药物或材料申请任何专利？
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这项工作没有任何直接或间接的资金支持。由作者自己承担责任。

Objectives: To demonstrate the changes seen in semaglutide patients before and after drug therapy and before and after a tailored approach with collagen stimulation in three different generations of patients.

Introduction: This article explores the potential of collagen stimulators such as PLLA-SCA (poly-L-lactic acid), Polydioxanone (PDO) threads, calcium hydroxylapatite (CaHA), and Albumin-platelet-rich fibrin (Alb-PRF) as therapeutic interventions to help combat the facial changes associated with semaglutide therapy in three patients from three different generations.

Materials / method: Standardized before-and-after comparison photos were taken using a ring light with a consistent brightness setting of 85% at a color temperature of 4600K. Each patient stood on a numbered floor mat, and the ring light was positioned precisely one inch from the mat to ensure uniform lighting conditions across sessions. A black backdrop was used to control for any potential reflective variance. Images were captured using an iPhone 4 with the TouchMD app at three angles: a straight-on view, a 45-degree angle, and a 90-degree side profile from each side.

Results: All three generations of patients with semaglutide use show an increased prominence of the nasolabial folds, sagging jowls, and loss of volume in the midface and temporal regions after several months of therapy. Eight weeks after collagen-stimulating treatments such as PLLA-SCA (poly-L-lactic acid), Polydioxanone (PDO) threads, calcium hydroxylapatite (CaHA), and Albumin-platelet-rich fibrin (Alb-PRF), these changes not only reverse, but the patient appears significantly improved as a result of the weight loss.

Conclusion: As rapid weight-loss trends, driven by the popularity of semaglutide and other GLP-1RAs, continue to rise, clinicians must remain proactive in addressing the non-metabolic side effects of these therapies. Combining personalized treatment plans and advanced collagen-stimulating modalities could redefine facial rejuvenation, offering patients an effective and natural means of countering the visible aging effects of rapid weight loss. Future research should further explore the interplay between collagen stimulators, muscle preservation strategies, and long-term aesthetic outcomes to optimize care

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这项工作没有任何直接或间接的资金支持。由作者自己承担责任。