Objectives: to identify current studies on the use of tranexamic acid in surgical procedures.
-to evaluate the possibility of using tranexamic acid for hair transplantation
-to identify the evidence on the best route of use of the medication - topical, oral or venous.
-to evaluate the risks and possible complications of tranexamic acid in hair transplant surgery patients
Introduction: Tranexamic acid is an inexpensive medication, used for several years to control bleeding in different situations. This medication acts on the fibrinolytic system to control perioperative bleeding. despite the old use, there are several uncertainties about the best route of drug administration. There is also great concern related to risk of thrombotic complications (deep vein thrombosis [DVT], pulmonary embolism [PE], myocardial infarction [MI], and cerebrovascular accident [CVA]) and seizures using this medicaton.
Materials / method: Bibliography related to the use of tranexamic acid in orthopedic and plastic surgeries and directly in hair transplant surgeries was reviewed. its use was analyzed in its topical, oral and intravenous.
Results: New studies seem to demonstrate that the use of tranexamic acid in hair transplantation is safe. the reviewed studies demonstrate safety in relation to the use of the drug, most of which demonstrate that there is no great risk of ischemic complications. its use can reduce the amount or even suspend the use of adrenaline in hair transplants in patients with a higher risk of ischemia and necrosis in the scalp. Topical use should be avoided for long durations due to the risk of seizures with prolonged use in this route of administration
Conclusion: There are few studies regarding the use of this drug in hair transplantation. new studies related to the best route of administration in relation to hair transplantation may make tranexamic acid a key medication for this type of surgery, providing a cleaner surgical field and faster procedures with better results for patients.
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