利益冲突声明

您有否接受任何资金来支持研究这个主题？
否

您是否接受过关于这项研究的任何酬金或其他报酬？
否

你是否和任何与您的研究所涉及的药物，材料或工具有密切联系的实体存在财务关系？
否

你是否拥有或者您已经为您此研究中的工具，药物或材料申请任何专利？
否

这项工作没有任何直接或间接的资金支持。由作者自己承担责任。

利益冲突声明

您有否接受任何资金来支持研究这个主题？
否

您是否接受过关于这项研究的任何酬金或其他报酬？
否

你是否和任何与您的研究所涉及的药物，材料或工具有密切联系的实体存在财务关系？
否

你是否拥有或者您已经为您此研究中的工具，药物或材料申请任何专利？
否

这项工作没有任何直接或间接的资金支持。由作者自己承担责任。

Objectives: - Understand the role of specific genetic markers, such as FTO, MCM6, and MC4R, in influencing BMI and weight loss outcomes.
- Explore the genetic factors that predict responses to dietary, endoscopic, and surgical weight loss interventions.
- Highlight the potential of genetic profiling in designing personalised strategies for improved health and aesthetic results, advancing the application of precision medicine in obesity management.

Introduction: Obesity, a multifactorial condition, presents significant challenges to health and aesthetics. Genetic factors are increasingly recognised for their role in influencing obesity risk and treatment outcomes. This study examines the impact of genetic profiling using a panel of single nucleotide polymorphisms (SNPs) to predict Body Mass Index (BMI) and weight loss responses across various interventions. The findings aim to advance personalised strategies that enhance health outcomes and aesthetic satisfaction.

Materials / method: A cohort of 9,372 patients was assessed for correlations between genetic markers and BMI, while 474 patients were evaluated for their response to weight loss interventions, including dietary plans, intragastric balloon procedures, and bariatric surgery. Key SNPs, such as rs9939609 (FTO), rs4988235 (MCM6), and rs2016520 (PPAR-Delta), were analysed for their impact on weight loss efficacy across treatments.

Results: SNPs like rs9939609 (FTO) and rs4988235 (MCM6) were strongly associated with higher BMI. Weight loss outcomes were significantly influenced by SNPs, with rs6544713 (ABCG8) correlating with dietary success, and MC4R-related SNPs predicting outcomes for surgical and endoscopic procedures. Personalised treatment plans based on genetic profiles demonstrated improved weight loss efficacy and enhanced patient satisfaction with aesthetic outcomes.

Conclusion: Genetic profiling reveals critical insights into obesity risk and weight loss responses, enabling the design of personalised interventions. By integrating genetic data into clinical practice, practitioners can optimise health outcomes and aesthetic satisfaction, marking a significant advancement in precision medicine for weight loss management.

利益冲突声明

您有否接受任何资金来支持研究这个主题？
否

您是否接受过关于这项研究的任何酬金或其他报酬？
否

你是否和任何与您的研究所涉及的药物，材料或工具有密切联系的实体存在财务关系？
否

你是否拥有或者您已经为您此研究中的工具，药物或材料申请任何专利？
否

这项工作没有任何直接或间接的资金支持。由作者自己承担责任。

Objectives: This study aims to demonstrate a minimally invasive approach to lipoabdominoplasty, assessing the benefits of robotic technology in the treatment of the muscular layer.

Introduction: In recent years, robotic surgery has expanded beyond traditional applications and is now emerging in aesthetic surgery. A significant advancement in this field is the development of the Minimally Invasive Robotic Endoscopic Lipoabdominoplasty (M.I.R.E.L.A.) technique, which builds upon the principles of the Minimally Invasive Laparoscopic Abdominoplasty (M.I.L.A.). Unlike M.I.L.A., which employs laparoscopic technology, M.I.R.E.L.A. integrates robotic-assisted surgery for the correction of rectus abdominis diastasis. This approach aims to enhance surgical precision while offering postoperative

Materials / method: A cross-sectional quantitative study was conducted through the evaluation of 20 patients who sought correction of diastasis via robotic surgery at the Sanfurgo Clinic in São Paulo, from July 2023 to June 2024.

Results: Out of the 20 patients, 19 had a history of previous pregnancies (95%). Additionally, 65% had an umbilical hernia, which was repaired during the procedure. 90% had a body mass index within normal limits, and 95% had a preoperative body fat percentage greater than 18%.

Conclusion: The findings provide valuable insights into the role of robotic surgery in plastic surgery, particularly for rectus abdominis diastasis correction, an area with limited existing literature. This technique shows potential for delivering optimal postoperative outcomes for patients while supporting the adaptation and skill development of plastic surgeons in this emerging field.

利益冲突声明

您有否接受任何资金来支持研究这个主题？
否

您是否接受过关于这项研究的任何酬金或其他报酬？
否

你是否和任何与您的研究所涉及的药物，材料或工具有密切联系的实体存在财务关系？
否

你是否拥有或者您已经为您此研究中的工具，药物或材料申请任何专利？
否

这项工作没有任何直接或间接的资金支持。由作者自己承担责任。

利益冲突声明

您有否接受任何资金来支持研究这个主题？
否

您是否接受过关于这项研究的任何酬金或其他报酬？
否

你是否和任何与您的研究所涉及的药物，材料或工具有密切联系的实体存在财务关系？
否

你是否拥有或者您已经为您此研究中的工具，药物或材料申请任何专利？
否

这项工作没有任何直接或间接的资金支持。由作者自己承担责任。