Objectives: Recently, thread lifting methods are more widely applied in dermatology and aesthetic surgery areas. The main idea of thread lifting was always fighting against soft tissues sagging – Anti ptosis. But there is not enough just shift the tissues mechanically for total face rejuvenation, it is required to influence the skin structure and quality as well.

Introduction: Unfortunately, chemical composition of the offered threads in the market (PDO, PDS, PGA, PLA, CL, Polypropylene, Silicone) is not provided with the required effect. As of today, the best substance for this matter is hyaluronic acid. Knowing this fact, almost every specialist is combining thread lifting procedure with hyaluronic acid injections.

Materials / method: Since 2016, we apply P(LA-CL) threads with hyaluronic acid additionally in the thread composition (thread formula looks as P(LA-CL)HA). We have performed more than 100 procedures for 55 patients. During this period some patients underwent the procedure twice or more. Mainly, threads were injected in the middle and lower face thirds per 5 threads per each side. Diameter of the thread is 2/0 with multi-directional barbs.

Results: We have also performed histological researches in rats comparing P(LA-CL) threads and P(LA-CL) threads with hyaluronic acid addition in the thread composition. The research lasted 1 year. Histological researches of P(LA-CL) threads and P(LA-CL)HA comparison have provided with the following results in favour of threads with hyaluronic acid:
- Decrease of inflammatory process and joint capsule around the thread
- Decrease of elastin around the thread from the first week of implantation
- Increase of I and III type of collagen for 55% and 20% accordingly

Conclusion: This research and the results in patients have showed the application of thread with hyaluronic acid hastens rehabilitation process after the procedure, excludes risk of subcutaneous scars appearance, increases development of elastin and collagen naturally influencing upon skin quality and structure. Application of threads with P(LA-CL)HA chemical composition and multidirectional barbs allows to receive as effect of replacing and soft tissues reposition as improvement of skin quality and structure.

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