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Objectives: To study the use of autologous conditioned plasma for facial rejuvenation

Introduction: Plasma is the liquid portion of whole blood. It is composed largely of water and proteins, and it provides a medium for red blood cells, white blood cells and platelets to circulate through the body. Platelets, also called thrombocytes, are blood cells that cause blood clots and other necessary growth healing functions.Platelet rich plasma has been used since more than a decade in dermatology and aesthetic applications.ACP is a breakthrough and is more efficacious than PRP and delivers better results.

Materials / method: In aesthetic practices Platelet-rich plasma (PRP) therapy is extensively used for antiageing and hair growth.As compared to PRP ,ACP requires Lower spin ,less trauma to cells allowing more stem cells to remain in the final PRF.ACP is spun at a lower speed, therefore no distinction of layers.Some wbcs and stem cells remain within the platelet layer that is collected for treatment. Thus has more healing factors than PRP.No anticoagulant. Creation of spongy fibrin matrix activates the platelets and allows for slow release of growth factors.It Has10 times the platelet concentration.

Results: - ACP delivers extremely gratifying results in reducing fine lines,
Periorbital rejuvenation and overall Skin toning and tightening,treating Acne scars, post traumatic scars and Stretch marks.Very promising results in Hair conditions like Androgenic Alopecia,Alopecia Areata, and Alopecia Barbae.
Promising treatment for Wound healing and non healing ulcers.

Conclusion: ACP is a more promising therapy than PRP.It is Less painful treatment,Has more concentration of Growth factors and Better Clinical, Histological & Aesthetic output

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Objectives: Antiaging is an internal process with external ramifications. A healthy body can maintain youth and beauty longer. Naturally released adipose tissue contents during different exercise modalities, can provide mesenchymal stem cells and hepatocytes which are involved in anti-inflammatory, reparatory, and detoxification processes reinstating liver function. Both aerobic and resistance exercises have been proven to be beneficial for patients with NAFLD.

Introduction: The adipose tissue produces an abundance of mesenchymal stem cells (MSCs). MSCs are at a rate of 1 in 100 in adipose tissue in contrast to 1 in 100,000 in the bone marrow. They are immune regulators, and proinflammatory inhibitors. MSCs are multipotent stem cells that can divide and develop into multiple specialized cell types. Adipose tissue derived MSCs contribute to the repair of vital organs such as the liver, heart, kidney, lung, and brain, via the delivery of signalling agents such as cytokines and growth factors [9] Anti-ageing and life itself depend on the health of vital organs

Materials / method: In this pilot clinical trial, we examined 10 individuals with NAFLD, 5 males and 5 females 54 - 64 years of age, who received 15 treatments with an effortless exercise technology, originally invented at London University for obesity and individuals who have difficulty performing strenuous workouts. The hypothesis was that the previously documented decrease of triglycerides and visceral fat creates the conditions for a series of biological reparative processes to be implemented.

Results: These include the natural release of adipose tissue contents into the bloodstream, supplying endogenous mesenchymal stem cells that differentiate into hepatocytes necessary for healthy liver functioning. Results supported the hypothesis of a possible release of endogenous MSCs by demonstrating a significant improvement of the NAFLD condition in ultrasonography reports along with optimal levels of ALT, AST, ALP, albumin, creatinine, bilirubin and CRP

Conclusion: These include the natural release of adipose tissue contents into the bloodstream, supplying endogenous mesenchymal stem cells that differentiate into hepatocytes necessary for healthy liver functioning. Results supported the hypothesis of a possible release of endogenous MSCs by demonstrating a significant improvement of the NAFLD condition in ultrasonography reports along with optimal levels of ALT, AST, ALP, albumin, creatinine, bilirubin and CRP

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Objectives: 1. Understand the biological properties of PRP.
2. Select PRP as mono or combination therapy depending on the indication.
3. Use a suitable application method / injection technique.
5. Perform photo documentation / quality control.

Introduction: The concept of body’s own rejuvenation is gaining more and more attention in aesthetic medicine and dermatology. PRP is a body's own substance that can be quickly prepared and applied on an outpatient basis.

Materials / method: Scientific databases (PubMed, Google Scholar) were reviewed for PRP and its application in the skin and scalp.

Results: A general body of evidence has recently emerged demonstarting positive response for PRP treatments for skin rejuvenation and treatment of alopecia. Intradermal injection of PRP alone or in combination with microneeding improves skin texture and thickens the epidermis. Hair regrowth can be induced by a series of PRP injections alone or in conjunction with microneedling or topical Minoxidil. The down time of CO2 laser is effectively reduced by both topical application of PRP and injection of PRP post laser. Melasma can be effectively treated by PRP and PRP plus microneedling.

Conclusion: PRP is a powerful tool for indications that focus on repair and healing (e.g. treatment of alopecia, scars, actinic elastosis, skin rejuvenation, melasma, atopic dermatitis). Regenerative procedures have found their role in daily practice next to the established treatment modalities.

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请注明名称（个人，公司，学会等等）: Arthrex GmbH

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