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Objectives: To review the phenomenon of wound-induced hair growth and the usefulness of therapeutic procedures based on skin wounding in androgenetic alopecia (AGA)

Introduction: Many studies have reported the role of hair follicles in the wound healing response, and vice versa, the creation of superficial injuries may stimulate hair growth, which has encouraged new treatments for hair loss.

Materials / method: A literature search was conducted to review cases of localized hypertrichosis induced by wounds and the role of micro needling, fractional laser, and scalp threading as mono therapy for AGA.

Results: Localized hypertrichosis has been extensively reported after bone fractures, burn injury, chronic venous ulcer, etc. Only 2 cases of wound-induced hair neogenesis in humans have been reported. As monotherapy for AGA, 1 of 3 studies of microneedling, 4 of 6 of fractional lasers and 2 of 3 of scalp threading show good efficacy.

Conclusion: Certain types of wounds seem to stimulate localized hair growth in humans, but the underlying mechanism is unclear. Reports of wound-induced hair follicle neogenesis in human are anecdotal and questions remain as to whether this is a true phenomenon in unman. Further clinical studies are needed before recommending wound-induced hair growth procedures as therapies for androgenetic alopecia (AGA)

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Objectives: To compare the efficacy of topical and oral minoxidil in treating androgenetic alopecia in Asian patients, utilizing a sample of ten individuals, and to assess the impact of transitioning from oral to topical minoxidil on treatment outcomes.

Introduction: Androgenetic alopecia (AGA), commonly known as male or female pattern baldness, is a prevalent form of hair loss affecting a significant proportion of the global population, including individuals of Asian descent. Among the available treatment options for AGA, minoxidil has emerged as a cornerstone therapeutic agent, demonstrating efficacy in promoting hair regrowth and arresting further hair loss.

Both topical and oral formulations of minoxidil have been extensively utilized in clinical practice, yet limited comparative data exist regarding their relative effectiveness, partic

Materials / method: Participants: Ten Asian AGA patients were divided into groups. Group A received topical minoxidil, Group B received oral minoxidil.

Procedure: Treatment lasted six months, with monthly follow-ups. Hair density, scalp coverage, and subjective feedback were assessed. Group B patients transitioning to topical were monitored for three months.

Analysis: Changes were compared within and between groups statistically. Limitations included small sample size and short follow-up.

Results: Oral minoxidil demonstrated fewer side effects and greater ease of adherence compared to topical formulations. Patients reported minimal adverse effects and found oral administration more convenient, potentially enhancing treatment compliance.

Conclusion: Both oral and topical minoxidil showed efficacy in treating Asian AGA patients. Oral minoxidil had fewer side effects and better adherence. Transition to topical minoxidil led to reduced efficacy. Larger, longer-term studies are needed for definitive conclusions on treatment outcomes.

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