Objectives: To give an overview on the potential adverse reactions to injectable fillers and their treatment.

Introduction: Adverse reactions to injectable fillers can be vascular or inflammatory. As most reactions are rare the clinical evidence behind treatment recommendations is limited.

Materials / method: Mostly emminence based.

Results: Vascular lesions are easy to diagnose. However, sometimes too late when pain was not present at time of injection. In case a hyaluronic acid (HA) based filler was used the treatment with hyaluronidase is mandatory. In inflammatory reactions – specifically when the filler used is not known - a diagnostics biopsy is a must. In case of an HA filler the treatment of choice is hyaluronidase accompanied by an immunomodulatory treatment. Despite all biofilm discussions in most of these reactions the sole use of an antibiotic is ineffective.

Conclusion: Adverse reactions to injectable fillers occur and will occur. Identification of the filler is mandatory as it the type of filler influences the treatment decisions. In case of adverse reactions to HA-fillers hyaluronidase is a must.

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Objectives: To understand the clinical presentations of possible nonvascular complications of mostly HA fillers, ways to prevent them, recognise them early and be able to treat them.

Introduction: Most of the discussion on complications of fillers center on vascular complications, as they are more drastic, although in terms of incidence non vascular complications are more common. It is important to be familiar with commonly encountered complications of mostly HA fillers, understand their causation, thereby be able to prevent most and treat the ones we encounter.

Materials / method: Non vascular complications can be classified according to timing of onset, or according to the nature of the complications – complications of placement, hypersensitivity and infections.
Complications will be discussed in detail, with illustrative cases encountered during practice , their etiology, course, clinical features , investigative modalities neede to diagnose, and possible treatment protocols and outcomes.

Results: It is easy to diagnose possible common complications of injectable fillers, provided one is familiar with them. With the exception of a few which are difficult to resolve, most case be easily treated.

Conclusion: As numbers of injectable procedures increases, so will we see an increase in number of complications. It will be a useful thing to know possible complications , ways to prevent them and also treat them.

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这项工作没有任何直接或间接的资金支持。由作者自己承担责任。