利益冲突声明

您有否接受任何资金来支持研究这个主题？
否

您是否接受过关于这项研究的任何酬金或其他报酬？
否

你是否和任何与您的研究所涉及的药物，材料或工具有密切联系的实体存在财务关系？
否

你是否拥有或者您已经为您此研究中的工具，药物或材料申请任何专利？
否

这项工作没有任何直接或间接的资金支持。由作者自己承担责任。

Objectives: The aim of this study is to optimize secondary intention wound healing after Mohs micrographic surgery (MMS) on ala nasi with an autolog patch formed from the patients own blood products: fibrin, platelets and leucocytes.

This initial case series demonstrates feasibility of using an autologous patch for wound closure on ala nasi after MMS.

Introduction: The face including ala nasi is a common site for skin cancer development. The reconstructive options after cancer surgery in the ala nasi region may be challenging and often healing by secondary intention is the best option even though it heals slow with risk of infection and scar contractures. Healing may be optimized by an autologous circular fibrin patch formed by the patient’s own blood, consisting of platelets, leucocytes and fibrin. The patch releases growth factors and stimulates granulation tissue.

Materials / method: Five patients diagnosed with primary nodular BCC on the ala nasi were treated after tumor margins were cleared by MMS. ⁠ Hemostasis was ensured prior grafting. Before closure a blood sample of 18 ml was drawn from the patient bedside in order to make the autologous patch. Wound healing was monitored by photographs for descriptive evaluation of esthetic outcome rated independently by two authors after 3-7 months. Evaluators rated the scars as excellent, good, acceptable or poor

Results: In general, excellent or good healing outcomes with a barely noticeable scar and with a satisfactory reestablishment of the anatomy, was seen on 3-7 months’ follow-up in all patients. In most cases the scars were rated as excellent or good, except one scar that was evaluated as acceptable. All patients tolerated the procedure well and no posttreatment complications was observed.

Conclusion: Autologous patch healing may provide essential improvement in healing of surgical defects and may be extrapolated in use to other concave areas in the face such as the temple and the nasofacial sulcus as well as convex areas. This initial case series demonstrates feasibility of using an autologous patch for wound closure on ala nasi after MMS. The procedure appears safe and no complications were reported at follow-up.

利益冲突声明

您有否接受任何资金来支持研究这个主题？
否

您是否接受过关于这项研究的任何酬金或其他报酬？
否

你是否和任何与您的研究所涉及的药物，材料或工具有密切联系的实体存在财务关系？
否

你是否拥有或者您已经为您此研究中的工具，药物或材料申请任何专利？
否

这项工作没有任何直接或间接的资金支持。由作者自己承担责任。

利益冲突声明

您有否接受任何资金来支持研究这个主题？
否

您是否接受过关于这项研究的任何酬金或其他报酬？
否

你是否和任何与您的研究所涉及的药物，材料或工具有密切联系的实体存在财务关系？
否

你是否拥有或者您已经为您此研究中的工具，药物或材料申请任何专利？
否

这项工作没有任何直接或间接的资金支持。由作者自己承担责任。

利益冲突声明

您有否接受任何资金来支持研究这个主题？
否

您是否接受过关于这项研究的任何酬金或其他报酬？
否

你是否和任何与您的研究所涉及的药物，材料或工具有密切联系的实体存在财务关系？
否

你是否拥有或者您已经为您此研究中的工具，药物或材料申请任何专利？
否

这项工作没有任何直接或间接的资金支持。由作者自己承担责任。

利益冲突声明

您有否接受任何资金来支持研究这个主题？
否

您是否接受过关于这项研究的任何酬金或其他报酬？
否

你是否和任何与您的研究所涉及的药物，材料或工具有密切联系的实体存在财务关系？
否

你是否拥有或者您已经为您此研究中的工具，药物或材料申请任何专利？
否

这项工作没有任何直接或间接的资金支持。由作者自己承担责任。

利益冲突声明

您有否接受任何资金来支持研究这个主题？
否

您是否接受过关于这项研究的任何酬金或其他报酬？
否

你是否和任何与您的研究所涉及的药物，材料或工具有密切联系的实体存在财务关系？
否

你是否拥有或者您已经为您此研究中的工具，药物或材料申请任何专利？
否

这项工作没有任何直接或间接的资金支持。由作者自己承担责任。