Objectives: a) Know currently available sources for information on psoriasis (most recent guidelines and reviews)
b) Know current treatment recommendations and underlying evidence on psoriasis
Introduction: Every year, new treatment options are available for the treatment of psoriasis. Keeping up with it all is a true challenge. Systematic reviews and guidelines can help for orientation and give guidance for specific clinical situations.
Materials / method: Extraction of key recommendations from current guidelines and systematic reviews.
Results: While topical treatments have seen little developments in the past, a total of 17 systemic treatments are licences in 2022 in Europe. Attempts to compare all treatments among other others by network metaanalysis show very good efficacy with regard to PASI 90 response for the newer treatment from the group of anti-Il23 and anti-Il 17 antibodies, with older treatments such as adalimumab and etanercept shower lower response rates.
Safety profiles and suitability in specific situations continue to shape with more experience with these drugs.
Conclusion: A trade-off between efficacy, safety and costs has to be consider to choose a treatment. Currently the more effective treatments tend to have a higher price in most countries.
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