Objectives: Reflectance confocal microscopy (RCM) and optical coherence tomography (OCT) are promising non-invasive imaging techniques, potentially able to decrease redundant biopsies in Skin oncology . RCM allows in vivo visualization of skin down to the papillary dermis at almost histological resolution, while OCT, particularly dynamic OCT (D-OCT), provides images deeper within the dermis and reveals the vascular pattern.

Introduction: Non-invasive reflectance confocal microscopy (RCM) and optical coherence tomography (OCT) have been used for skin cancer diagnosis and extended to the dermo-cosmetic field, for skin pathophysiology understanding and therapeutics monitoring

Materials / method: A review of all the possible uses of RCM and OCT both in oncology and in cosmetology is made and as a monitoring of therapies and new treatments

Results: RCM and OCT have been shown to improve diagnostic accuracy in skin cancer diagnosis , avoid unnecessary excision .
Also in Cosmetology and in monitoring new therapies , RCM and OCT has been shown an excellent applicability able to interpret structures and changes in aging and in cosmetology monitoring

Conclusion: RCM and OCT demonstrate high performance in skin oncology and in dermo-cosmetic research and practice.

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Objectives: We intended to find out if Laser treatments, ablative and non-ablative as monotherapy or in combination can represent a meaningful treatment options in selected cases.

Introduction: With a clear increase in the incidence and a continuously earlier onset, the
treatment options for localized resectionable basal cell carcinoma
include micrographically controlled surgery, simple excision, curettage, laser ablation,
cryosurgery, imiquimod, 5-fluorouracil, photodynamic treatment and radiotherapy.
Nonsurgical treatment options are more suited for cases in which surgical procedures lead to disfigurement or functional impairments or for patients with a high surgical risk. Laser treatment, ablative and non-ablative as monotherapy or in combination can represent a meaningful tre

Materials / method: IN pub med and and multiple journals we searched for the use of lasers in NMSC , esp. BCC, their paramenters and results.

Results: Laser ablation with Er:YAG and CO2 lasers continues to be of interest as a potentially less invasive alternative to surgery for the treatment of low-risk superficial and nodular subtypes of BCCs. The lack of histopathological confirmation has been a limitation but a reflectance confocal microscopy (RCM) imaging-guided approach offers cellular-level histopathology-like feedback directly on the patient.
Ablative fractional lasers (AFXL) enhance uptake of topical therapeutics and the concept of fractional laser-assisted drug delivery has now been taken into clinical practice using 5 FU, Imiquimod

Conclusion: In recent years there has been an increase in evidence about the effects of laser treatment of basal cell carcinoma; nevertheless, further studies with a high level of evidence are necessary.

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Objectives: to understand medical conditions that have photosensitivity
to discuss the evidence on available oral photoprotection and its indications

Conclusion: Photoprotection is essential for skin health.
There are dermatoses that are exacerbated or appear with UVR
Oral photoprotection is a promising but still unmet need, especially in concomitance with other protection measures.

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