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Objectives: The purpose of this presentation is to provide evidence-based medicine on their uses in aesthetic medicine.

Introduction: The use of exosomes has increased significantly over the past several years in aesthetic medicine. There is a myriad of potential uses for these extracellular vesicles that promote intracellular communication. The purpose of this presentation is to provide evidence-based medicine on their uses in aesthetic medicine.

Materials / method: Methods: Literature review looking at the current publications in the exosome space was used.

Results: At present, the current literature landscape for the use of exosomes in medical dermatology and aesthetics is small. The published data supports that wound healing is enhanced with the use of exosomes and that within aesthetics, procedures can heal faster than traditional therapy as well as accelerating hair growth in many individuals.

Conclusion: Exosomes have incredible potentials in dermatology and in aesthetic medicine. We must demand that appropriate clinical trials are performed to verify the current hype surrounding these products and determine how best to use them to benefit our patients.

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Objectives: Define hybrosomes.
Explain why hybrasomes are more powerful than exosomes alone.
Present scientific data on how telomerase is affected by hybrasomes and alter cell aging

Introduction: Hybrosomes are bio-engineered exosomes. By combining cord blood exosomes with a liposomal agent, a more powerful compound has been developed. Herein, we describe the methods of membrane fusion, demonstrate the effectiveness of hybrosomes and show for the first time, changes in cellular telomerase activity, indicating reversal of aging on the cell level.

Materials / method: Using a patent pending membrane fusion technology, a bovine cord blood exosome has been hybridized with a liposomal agent to create what is called a Hybrosome.

Results: In addition to numerous randomized, double blinded studies showing the effectiveness of Hybrosomes, cell culture of aged fibroblasts revealed a significantly increased level of telomerase enzyme, indicating a reversal of cell aging.

Conclusion: Hybrosomes as well as Plantosomes demonstrated increases in telomerase enzyme activity, indicating reversal of cell aging in skin fibroblasts.

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请注明名称（个人，公司，学会等等）: co-founder, board member, shareholder, Mage Biotechnologies

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