2025 英卡思巴黎国际年会
大会日程

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请注明名称（个人，公司，学会等等）: Jetema and Xytide Biotech

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请注明名称（个人，公司，学会等等）: Jetema and Xytide Biotech

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这项工作的完成感谢以下机构的支持： Jetema and Xytide Biotech

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这项工作的完成感谢以下机构的支持： Jetema

Objectives: 1. To understand that the midfacial aging is multifactorial which cannot be fixed completely by volume replacement only.
2. To prove that 3 'R' technique is an effective approach for midface rejuvenation in the Asian population.
3. To evaluate a long-term F/U after combined procedures of HA filler injections and PDO thread lifting.

Introduction: The combination of hyaluronic acid (HA) fillers and polydioxanone (PDO) thread lifting is gaining popularity for midface rejuvenation, especially among the Asian population. Despite the common use of these techniques, there is a paucity of long-term studies assessing their combined efficacy and safety. This study aims to evaluate the efficacy and safety of combined HA filler and PDO thread treatment for midface rejuvenation over a 24-month period in a Korean population.

Materials / method: This prospective, blinded, single-center, open-label trial included 11 Korean subjects, aged 29–70 years, with mid- face volume loss graded 1–4 on the anteromedial cheek fullness scale. Participants were treated with crosslinked HA dermal fillers and PDO threads using 3’R’ technique. Assessments were conducted using the Global Aesthetic Improvement Scale (GAIS), investigator-led clinical evaluations, and volumetric measurements using the Morpheus 3D system at baseline, 6, 12, and 24 months post-treatment.

Results: Quantitative analysis revealed a significant reduction in midface width from an average baseline of 149.27–145.00 mm at 24 months (p < 0.00001). Similarly, lower face width decreased from 130.36 to 117.27 mm at 24 months (p < 0.00001). The GAIS scores demonstrated high levels of subject satisfaction, with 9 out of 11 patients reporting consistent satisfaction or improvement over 24 months. Minimal adverse events were reported, and no serious complications occurred.

Conclusion: 1. The combination of HA fillers and PDO threads was effective in achieving and maintaining long-term improvements in facial volume and contour.
2. The Morpheus 3D system provided objective volumetric data, which supported the subjective improvements observed by patients and investigators.
3. The study results highlight the benefits of ongoing neocollagenesis and tissue remodeling beyond the dissolution period of the materials.

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这项工作没有任何直接或间接的资金支持。由作者自己承担责任。