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IMCAS Academy

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IMCAS Americas 2025
Program

030

Contributing lectures: Lasers & EBDs

Room: Room 5
Date: Friday 11 April 2025 at 11:00 to 12:00
Format: CONTRIBUTED TALKS > session made up of abstract submissions that were carefully reviewed and selected by the Scientific Board

Chairs

Dr Tulia COPETE

Dermatologist

Colombia

Dr Fabian PEREZ RIVERA

Plastic Surgeon

Argentina

Lectures of the session

Hours	Speakers	Lecture title	Abstract	Number
11:00	Dr Arminda AVDULAJ	Combined treatment: Dual wavelength laser for post-acne scar treatment & PRP	View	143810
11:12	Dr Amanda Mirella KIYOMURA DE PAULA	Enhanced outcomes in cellulite treatment: Combining assisted subcision with long-pulsed laser for hematoma management and hyperpigmentation prevention	View	143812
11:24	Dr Fernanda AMARO FERRAZ PIZARRO	The new era of regenerative therapy: Exosomes associated with PDRN in the prevention and treatment of oxidative stress-induced skin aging		143813
11:36	Dr Natthachat JURAIRATTANAPORN	The application of microneedle radiofrequency for pigmentary conditions	View	148218
11:48		Q&A		143815

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Lasers

Combined treatments

Drug delivery

Platelet-rich plasma (PRP)

Scars

Dr Arminda AVDULAJ

Albania

Other author(s) :

Combined treatment: Dual wavelength laser for post-acne scar treatment & PRP

Objectives: This study aims to share the authors' experience using a dual wavelength laser combined with PRP (LADD) for treating post-acne scars.

Introduction: Post-acne scars present a long-standing challenge in dermatology and aesthetic medicine. However, recent technological advancements have provided various treatment options for improving both the appearance of acne scars and the overall skin texture and tone. Among these, laser treatments—especially fractional ablative and non-ablative lasers—have proven effective in scar reduction. When combined with Platelet-Rich Plasma (PRP), delivered through LADD via microchannels created by the laser, the treatment not only accelerates recovery but also enhances overall results.

Materials / method: This retrospective study was conducted in two clinics in Albania, involving 38 patients with post-acne scarring. Patients were evaluated before treatment and 3 months after the final session. The treatment consisted of a hybrid approach combining fractional ablative CO2 laser and fractional non-ablative 1570 nm wavelength laser, immediately after the laser treatment, PRP was applied using Laser Assisted Drug Delivery (LADD). Scar improvement was assessed using two standardized qualitative tools: the Vancouver Scar Scale (VSS) and the Patient and Observer Scar Assessment Scale (POSAS).

Results: Among the 38 patients, a significant reduction in both VSS and POSAS scores was observed, with a reduction of 71.9% ± 14.4% in VSS and 67.1% ± 8.4% in POSAS. The follow-up period ranged from 3 to 6 months, and no serious adverse events were reported.

Conclusion: This study demonstrates that the combination of a hybrid fractional ablative and non-ablative laser approach with PRP delivered through LADD is a safe and effective modality for the treatment of post-acne scars. The results indicate significant improvement in scar appearance, high patient satisfaction, and a favorable safety profile.

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability

Dr Amanda Mirella KIYOMURA DE PAULA

Brazil

Other author(s) :

Enhanced outcomes in cellulite treatment: Combining assisted subcision with long-pulsed laser for hematoma management and hyperpigmentation prevention

Objectives: To evaluate the benefits of combining assisted subcision with long-pulsed laser photobiomodulation for reducing hematomas and preventing hemossiderin-induced hyperpigmentation in cellulite treatments, with the goal of enhancing patient satisfaction and self-esteem.

Introduction: Cellulite, affecting most women, causes skin dimpling and impacts self-esteem. Assisted subcision effectively releases fibrous septae and stimulates collagen for smoother skin texture. However, post-procedural hematomas are common and may lead to hyperpigmentation. Integrating long-pulsed laser (1064 nm) photobiomodulation accelerates recovery by targeting hemoglobin chromophores, reducing hematomas, and minimizing aesthetic risks.

Materials / method: Cases observed in clinical practice involved patients with cellulite undergoing assisted subcision, followed by long-pulsed laser photobiomodulation (1064 nm). The protocol used 10-15 J/cm² fluence, tailored pulse durations based on hematoma density, and ≤ 0.5W power. The laser targeted cytochrome c oxidase in mitochondria, enhancing ATP production to accelerate hematoma absorption and prevent pigmentation, aiming to optimize post-treatment aesthetic outcomes.

Results: Patients demonstrated rapid hematoma resolution following the combined treatment of assisted subcision with long-pulsed laser. After two sessions, most cases showed minimal ecchymosis and no signs of hemossiderin-induced hyperpigmentation. The laser treatment effectively minimized discoloration and inflammation, leading to a smoother and more uniform skin tone. Patients reported high satisfaction with the aesthetic results, noting faster recovery and increased confidence due to the absence of lingering pigmentation issues.

Conclusion: The combination of assisted subcision and long-pulsed laser proved effective in accelerating hematoma resolution and preventing hyperpigmentation, enhancing both aesthetic and psychological outcomes. The integrated approach facilitated a faster recovery with improved skin uniformity, reinforcing patient confidence and satisfaction with cellulite treatment.

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability

Dr Fernanda AMARO FERRAZ PIZARRO

Dermatologist

Brazil

Other author(s) : Dra. Fernanda Amaro Ferraz Pizarro

The new era of regenerative therapy: Exosomes associated with PDRN in the prevention and treatment of oxidative stress-induced skin aging

Objectives: This review aims to evaluate the combined efficacy of exosomes and PDRN in treating skin aging induced by oxidative stress. By exploring their mechanisms of action, the review highlights their potential to mitigate reactive oxygen species (ROS)-induced damage, promote collagen production, and enhance skin regeneration.

Introduction: Oxidative stress is a key factor in skin aging, caused by an excess of reactive oxygen species (ROS) that damage cellular structures. This process accelerates collagen degradation, inflammation, and loss of elasticity. Emerging therapies such as exosomes and PDRN offer innovative solutions by combating oxidative damage and promoting tissue regeneration.

Materials / method: Recent literature, including clinical trials and experimental studies, was reviewed to evaluate the efficacy of exosomes and PDRN in skin aging. Key metrics such as collagen synthesis, inflammation reduction, and extracellular matrix regeneration were analyzed. The review also integrates lifestyle factors such as diet, antioxidants, and sun protection.

Results: Exosomes effectively reduce inflammation and stimulate fibroblast activity, while PDRN enhances angiogenesis and extracellular matrix repair. Combined, they deliver superior results in improving skin elasticity, reducing wrinkles, and reversing oxidative damage. Lifestyle interventions further amplify these effects, optimizing therapeutic outcomes.

Conclusion: The integration of exosomes and PDRN into dermatological practice represents a breakthrough in addressing oxidative stress-induced skin aging. Their synergistic effects, combined with healthy lifestyle habits, offer a holistic approach to prevention and treatment, setting a new standard for regenerative therapies.

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability

Dr Natthachat JURAIRATTANAPORN

Dermatologist

Thailand

Other author(s) :

The application of microneedle radiofrequency for pigmentary conditions

Objectives: This lecture explores the innovative treatment of microneedle radiofrequency (MNRF) for pigmentary lesions, with a focus on melasma. Discover how MNRF combines microneedling and radiofrequency energy to precisely target melanin deposits and stimulate collagen, leading to significant improvements in skin tone and texture. Real patient cases will showcase the effectiveness of MNRF in reducing the appearance of melasma and other pigmentary concerns. Learn about the latest research, treatment protocols, and patient selection criteria for optimal results.

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability

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IMCAS Americas 2025 Program

030

Contributing lectures: Lasers & EBDs

Chairs

Lectures of the session

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IMCAS Americas 2025
Program