Objectives: Reflectance confocal microscopy (RCM) and optical coherence tomography (OCT) are promising non-invasive imaging techniques, potentially able to decrease redundant biopsies in Skin oncology . RCM allows in vivo visualization of skin down to the papillary dermis at almost histological resolution, while OCT, particularly dynamic OCT (D-OCT), provides images deeper within the dermis and reveals the vascular pattern.

Introduction: Non-invasive reflectance confocal microscopy (RCM) and optical coherence tomography (OCT) have been used for skin cancer diagnosis and extended to the dermo-cosmetic field, for skin pathophysiology understanding and therapeutics monitoring

Materials / method: A review of all the possible uses of RCM and OCT both in oncology and in cosmetology is made and as a monitoring of therapies and new treatments

Results: RCM and OCT have been shown to improve diagnostic accuracy in skin cancer diagnosis , avoid unnecessary excision .
Also in Cosmetology and in monitoring new therapies , RCM and OCT has been shown an excellent applicability able to interpret structures and changes in aging and in cosmetology monitoring

Conclusion: RCM and OCT demonstrate high performance in skin oncology and in dermo-cosmetic research and practice.

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability

Disclosures

Did you receive any funding to support your research for this TOPIC?
Yes
Please specify entities (individual, company, society): Galderma

Were you provided with any honoraria, payment or other compensation for your work on this study?
Yes
Please specify entities (individual, company, society): Personal

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work is presented thanks to the support of: SIDEMASK by victor

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability

Objectives: We intended to find out if Laser treatments, ablative and non-ablative as monotherapy or in combination can represent a meaningful treatment options in selected cases.

Introduction: With a clear increase in the incidence and a continuously earlier onset, the
treatment options for localized resectionable basal cell carcinoma
include micrographically controlled surgery, simple excision, curettage, laser ablation,
cryosurgery, imiquimod, 5-fluorouracil, photodynamic treatment and radiotherapy.
Nonsurgical treatment options are more suited for cases in which surgical procedures lead to disfigurement or functional impairments or for patients with a high surgical risk. Laser treatment, ablative and non-ablative as monotherapy or in combination can represent a meaningful tre

Materials / method: IN pub med and and multiple journals we searched for the use of lasers in NMSC , esp. BCC, their paramenters and results.

Results: Laser ablation with Er:YAG and CO2 lasers continues to be of interest as a potentially less invasive alternative to surgery for the treatment of low-risk superficial and nodular subtypes of BCCs. The lack of histopathological confirmation has been a limitation but a reflectance confocal microscopy (RCM) imaging-guided approach offers cellular-level histopathology-like feedback directly on the patient.
Ablative fractional lasers (AFXL) enhance uptake of topical therapeutics and the concept of fractional laser-assisted drug delivery has now been taken into clinical practice using 5 FU, Imiquimod

Conclusion: In recent years there has been an increase in evidence about the effects of laser treatment of basal cell carcinoma; nevertheless, further studies with a high level of evidence are necessary.

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability

Objectives: to understand medical conditions that have photosensitivity
to discuss the evidence on available oral photoprotection and its indications

Conclusion: Photoprotection is essential for skin health.
There are dermatoses that are exacerbated or appear with UVR
Oral photoprotection is a promising but still unmet need, especially in concomitance with other protection measures.

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work is presented thanks to the support of: SIDEMAST by victor