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IMCAS Asia 2025
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Contributed Talks: Aesthetics in all its forms

Room: Room 6 - Level 3
Date: Sunday 8 June 2025 at 16:00 to 17:00
Format: CONTRIBUTED TALKS > session made up of abstract submissions that were carefully reviewed and selected by the Scientific Board

Chairs

Dr Hugues CARTIER

Dermatologist

France

Dr Chatbongkoch KHEMACHEEWAKUL

Dermatologist

Thailand

Lectures of the session

Hours	Speakers	Lecture title	Abstract	Number
16:00	Dr Florencia DE LOS SANTOS	Neuroaesthetics and facial harmonization: Image, self-esteem, and mental health	View	147209
16:12	Dr Atsuko YANAGAWA	Clinical use of polynucleotide with mannitol in Japanese patients: Case studies from our clinic	View	149238
16:24	Dr Rosalyn KUPWIWAT	The benefits of polynucleotides, HA, and mannitol in skin therapy	View	149380
16:36	Dr Elona GABUEVA	Full face botulinum therapy	View	149455
16:48		Q&A		147213

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Dr Florencia DE LOS SANTOS

Uruguay

Other author(s) : Dr. Florencia de los Santos

Neuroaesthetics and facial harmonization: Image, self-esteem, and mental health

Objectives: This presentation aims to explore the scientific foundations of facial harmonization through the lens of neuroaesthetics. It will examine how facial proportions and symmetry impact brain perception, self-image, and emotional well-being. The session will provide medical insights into the role of aesthetic interventions in improving self-esteem and promoting mental health, based on current evidence and clinical experience.

Introduction: Facial harmonization has evolved beyond aesthetic enhancement to become a tool for improving self-perception and emotional well-being. Grounded in neuroaesthetics, this presentation explores how the brain processes facial balance and beauty, and how medical interventions can positively influence self-esteem and mental health. Understanding the neurobiological impact of facial aesthetics opens new dimensions in patient-centered care.

Materials / method: A narrative review of scientific literature was conducted, focusing on recent studies related to neuroaesthetics, facial harmonization, and their psychological impact. In addition, clinical insights are drawn from over 10 years of medical experience in aesthetic medicine, integrating evidence-based practice with real-world patient outcomes.

Results: Scientific literature confirms that facial symmetry, proportion, and balance positively influence neural reward circuits and self-perception. Clinically, patients undergoing facial harmonization report increased self-esteem, improved emotional well-being, and enhanced social confidence. These outcomes support the role of facial aesthetics as a therapeutic tool beyond beauty, contributing to mental health and quality of life.

Conclusion: Facial harmonization, when approached from a neuroaesthetic and clinical perspective, transcends cosmetic goals. It becomes a valuable medical intervention to support self-esteem and emotional well-being. Understanding the neurological and psychological impact of aesthetic treatments allows for more comprehensive, patient-centered care. Beauty, in this context, is not superficial—it is a reflection of internal balance and health.

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability

Dr Atsuko YANAGAWA

Japan

Other author(s) :

Clinical use of polynucleotide with mannitol in Japanese patients: Case studies from our clinic

Objectives: To define optimal patient selection criteria for polynucleotide with mannitol injections, and to explore the clinical benefits of combining this treatment with amino acids and energy-based devices for enhanced outcomes.

Introduction: During the COVID-19 pandemic, prolonged mask usage contributed to an increase in facial erythema and inflammatory skin conditions among Japanese patients. Polynucleotide with mannitol, known for its anti-inflammatory and regenerative properties, proved to be especially beneficial in these cases. In our clinic, we incorporated additional amino acids and device-based therapies to further optimize treatment efficacy and improve skin quality.

Materials / method: Polynucleotide with mannitol injectables were administered to patients with persistent facial redness and inflammation. In selected cases, treatment was combined with amino acid supplementation and energy-based devices to enhance results.
Clinical documentation included imaging by iPad (Apple Inc.), CASIO Derma Camera, dermascope, SONY α7 mirrorless camera, re-Beau (Japan), and Quantificare 3D system (Face/Body).

Results: Over 40Japanese patients were included. In elderly patients, diminished cutaneous amino acid levels necessitated supplementation to achieve comparable outcomes. Across the cohort, the combination of polynucleotide with mannitol, amino acids, and device-based therapy showed superior improvement in skin texture, redness, and overall dermal health compared to monotherapy.

Conclusion: This presentation will share clinical insights from real-world case studies in Japanese patients, emphasizing effective patient selection and treatment strategies. The integration of polynucleotide with mannitol injections, amino acids, and energy-based devices offers a comprehensive approach to managing inflammatory skin concerns and promoting long-term skin regeneration.

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability

Dr Rosalyn KUPWIWAT

Dermatologist

Thailand

Other author(s) :

The benefits of polynucleotides, HA, and mannitol in skin therapy

Objectives: This presentation aims to review the current literature on the use of polynucleotides in various dermatological conditions and share clinical insights from real-world applications.

Introduction: Polynucleotides (PNs) have gained attention in dermatology and aesthetic medicine due to their regenerative properties, enhancing tissue repair, hydration, and collagen synthesis. When combined with hyaluronic acid (HA) and mannitol, their efficacy in skin rejuvenation and wound healing may be further optimized.

Materials / method: A comprehensive literature review was conducted to assess the efficacy of polynucleotides in different skin conditions, including aging, scarring, and post-procedural healing. Additionally, a clinical protocol incorporating polynucleotides, HA, and mannitol will be presented alongside notable case studies demonstrating patient outcomes

Results: Emerging evidence supports the role of polynucleotides in improving skin quality, reducing inflammation, and enhancing cellular repair. Our clinical experience further highlights their potential in optimizing treatment outcomes in aesthetic and therapeutic dermatology.

Conclusion: Polynucleotides, in combination with HA and mannitol, offer a promising approach for skin therapy. This session will provide an evidence-based review and practical guidance for incorporating these agents into clinical practice.

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability

Dr Elona GABUEVA

Dermatologist

Russia

Other author(s) :

Full face botulinum therapy

Objectives: Botulinum therapy has long been more than just a procedure for treating wrinkles. Botulinum toxin is the most wonderful molecule of the 20th century. With its help, we can change the faces of our patients. Change the position of the eyebrows, reduce the nose, push up the lip effect, improve the contours of the face, make the face thin and much more.

Introduction: If we take into account all the anatomical features and topographic anatomy and biomechanics of facial muscles, we can significantly influence their work. And for these purposes, I use the Full Face technique, when I inject facial facial and chewing muscles in a complex.

Materials / method: In the Full Face technique, it is very important to maintain a dose balance between levator muscles and depressors, in favor of depressors. Injections are carried out in a multifocal technique into facial muscles, including the auricular muscles (which few people mention), but with which you can achieve eyebrow lifting. As well as techniques for injecting botulinum toxin into the orbicularis oris muscle of the mouth for a push-up effect , a tarsal portion of the orbicularis oculii muscle of the eye to change the eye section, into a masseter to make the face thin, into a platizma.

Results: In the report, I want to demonstrate a video of full face botulinum therapy techniques that I have been using in my practice for more than 7 years and get very aesthetic results.

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability

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IMCAS Asia 2025 Program

Contributed Talks: Aesthetics in all its forms

Chairs

Lectures of the session

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IMCAS Asia 2025
Program