Atchima SUWANCHINDA's публикаций (28)

Polynucleotides as a novel therapeutic approach in androgenetic alopecia: an analysis of effectiveness and safety.

Feb, 2025

Androgenetic alopecia (AGA) is a highly prevalent condition that poses a significant challenge to quality of life, yet the US Food and Drug Administration-approved treatments remain limited. Polynucleotides (PN) stimulate tissue regeneration by reducing inflammation, activation of growth factors and accelerating angiogenesis, which are vital for hair regrowth. This study aimed to assess the efficacy of PN in promoting hair regrowth by measuring changes in hair diameter and density in patients with AGA. This prospective study evaluated 28 patients with AGA who received four injection of DOT™ PN (DNA Fragment Optimizing Technology Polynucleotides) at four-week intervals. Hair diameter and density were quantitatively assessed using dermoscopic analysis. Treatment efficacy was also evaluated using patient and dermatologist satisfaction survey. Both hair diameter and density showed significant improvement, with hair diameter increased notably one month post-treatment and continuing to rise throughout the study. Total hair density improvements were evident from one months post-treatment onwards. Additionally, the dermatologist's assessment indicated stabilization in 60.7% of cases, while the patient assessment score indicated improvement in 82.1% of cases, with no serious side effects. This study demonstrates that PN effectively promotes hair regrowth in AGA patients. This is likely due to increased angiogenesis and anti-apoptotic effects. PN offers a promising new alternative for patients who have not responded to traditional treatments. Подробнее

Archives of dermatological research

Needle Radiofrequency Combined with Topical Exosome Therapy for Moderate to Severe Acne.

Jan, 2025

This case series aims to evaluate the efficacy, patient satisfaction, and safety of combined needle radiofrequency (RF) and topical exosome therapy for moderate to severe acne. Подробнее

Life (Basel, Switzerland)

Reverse and antegrade vector thread lifting techniques: Correcting nasolabial and marionette lines.

Dec, 2024

This study evaluates the efficacy of reverse and antegrade thread lifting vectors in conjunction with thread selection for correcting nasolabial folds and marionette lines, aiming to enhance treatment precision and effectiveness. Подробнее

Journal of cosmetic dermatology Загрузить больше  

Non-surgical rhinoplasty through minimal invasive nose thread procedures: Adverse effects and prevention methods.

Feb, 2024

This review addresses the intricacies of non-surgical rhinoplasty, particularly focusing on the utilization of absorbable sutures known as "Volumizing threads" in combination with fillers. The aim is to explore the enhanced precision of nasal contouring offered by these combined procedures compared to sole filler injections. Подробнее

Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)

Nonscarring alopecia after temporal lifting technique with dermal fillers.

Jul, 2023

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JAAD case reports

Case series of tongue necrosis from vascular complications after chin augmentation with hyaluronic acid: Potential pathophysiology and management.

Mar, 2023

Even though the chin is considered a safe injection area for facial filler augmentation, tongue necrosis is a rare complication in this area. Подробнее

Journal of cosmetic dermatology

The efficacy and safety of the innovative cold atmospheric-pressure plasma technology in the treatment of striae distensae: A randomized controlled trial.

Dec, 2022

Available current therapeutics modalities for striae distensae (SD) provide inconsistently effective outcomes. There is ongoing research on innovative treatment modalities to find better treatment solutions. Подробнее

Journal of cosmetic dermatology

Efficacy and safety of the innovative cold atmospheric-pressure plasma technology in the treatment of keloid: A randomized controlled trial.

Dec, 2022

Keloid (KD) treatment is challenging for both physicians and patients. It can be functional debilitating and psychologically distressing. Available current therapeutics modalities give inconsistently effective results. Подробнее

Journal of cosmetic dermatology

A novel technique in reducing sebum production and improving atrophic acne scars.

Nov, 2022

Fractional microneedling radiofrequency (FMR) has gained popularity for the treatment of acne scars, owing to favorable outcomes and short downtimes. This study aimed to investigate FMR use in reducing facial sebum production and treating acne scars. Подробнее

Journal of cosmetic dermatology

Outcomes of 1064-nm picosecond laser alone and in combination with fractional 1064-nm picosecond laser in tattoo removal.

Jul, 2022

Removal of the unwanted tattoo was initially focused treatment of picosecond laser in the setting of the unfractionated beam, whereas the fractionated 1064-nm picosecond lasers (Fr-Pico) has been successfully utilized in various skin conditions, including scar and benign pigmented lesions. However, no studies compared the combination of Fr-Pico and unfractional 1064-nm picosecond laser (UFr-Pico) and UFr-Pico alone in tattoo removal. Подробнее

Journal of cosmetic dermatology

Validated 5 - Point photonumeric scales for the assessment of hand atrophy.

Mar, 2022

Quantifying the degree of dorsal hand atrophy is a challenging endeavor, but often necessary, in both the clinical and the research setting. The aim of this investigation was to create and consecutively validate a 5-point photonumeric scale for assessment of dorsal hand atrophy. Подробнее

Journal of cosmetic dermatology

Validated 5-point photonumeric scales for the assessment of the jowls and chin.

Feb, 2022

The objective of this investigation was to create and to examine the reproducibility and validity of 5-point photonumeric assessment scales that allow objective assessment of chin retrusion and jawline sagging using a digital and a live validation. Подробнее

Journal of cosmetic dermatology

Validated 5-point photonumeric scales for the assessment of the periorbital region.

Jan, 2022

The objective of this investigation was to create and validate 5-point photonumeric scales for the assessment of dynamic crow's feet, static crow's feet, and infraorbital hollows. Подробнее

Journal of cosmetic dermatology

Customized Treatment Using Microfocused Ultrasound with Visualization for Optimized Patient Outcomes: A Review of Skin-tightening Energy Technologies and a Pan-Asian Adaptation of the Expert Panel's Gold Standard Consensus.

May, 2021

Noninvasive facial-rejuvenation devices, such as nonablative radiofrequency (RF) and laser-assisted technology, are increasingly replacing higher-risk surgeries for face and body skin laxity. We sought to review published information on noninvasive energy device safety and efficacy in aesthetic skin tightening, compare these with our experiences in Asian patients, and disseminate a consensus for optimizing microfocused ultrasound with visualization (MFU-V) in Asian patients. A broad, nonexhaustive, nonsystematic literature search of published studies indexed in PubMed was performed to compare selected energy technologies to MFU-V for noninvasive face and body skin tightening, in particular, among Asian patients. This was supplemented with internal documents to provide evidence and support arguments if no peer-reviewed data were available. We highlighted the differences between devices and platforms and identified factors requiring attention and caution. Due to the increase in new devices lacking strong supporting clinical evidence of both safety and efficacy in Asia, it is necessary to convene physicians with substantial experience in MFU-V and devise a consensus on Asian patient selection, treatment planning, and customization. Many platforms duplicate or claim similar technologies, efficacy, or safety without significant peer-reviewed scientific or clinical evidence. We showed that MFU-V satisfies this clinical imperative. Further, the patented DeepSEE technology allows users to noninvasively "see" through the skin to ensure treatment precision, facilitate optimal skin lifting and tightening, and enhance patient comfort and safety. Therefore, we believe that MFU-V is the gold standard for nonsurgical lifting and skin tightening. Подробнее

The Journal of clinical and aesthetic dermatology

Case Report: The role of intradermal micro-droplet hyaluronic acid injection in the correction of filler nodules complication.

Nov, 2020

Filler injection has been widely used as a non-surgical intervention for skin rejuvenation and augmentation for the past decade. Hyaluronic acid (HA) is considered the most common treated material with high safety profile. Various mechanisms, including promoting collagen synthesis are postulated the efficacy of this powerful skin rejuvenation. The greater number of its used, the more complications were seen. Among the non-vascular complications from filler injection, the most frequent one is nodule formation. It could occur as early or late onset even with HA injection. One of the causes of these nodule formation is from poor injection technique leading to visible skin beads and lumps. The current treatments of these filler side effects mainly aim to remove or reduce excessive or displaced filler product. To the best of our knowledge, there has been no report of using the intradermal injection of the micro-droplet HA to correct filler nodule and simultaneously revitalize the skin quality. This novel treatment technique could be a safe alternative for nodule formation correction. Подробнее

Dermatologic therapy

The six different injection techniques for the temple relevant for soft tissue filler augmentation procedures - Clinical anatomy and danger zones.

Jul, 2020

The most promising facial region for inducing pan-facial effects is the temporal region. The temple displays signs of facial aging itself which include temporal volume loss and increased visibility of the temporal crest, the temporal vasculature, the lateral orbital rim, and the upper zygomatic arch. The objective of this article is to provide a detailed review of temple anatomy pertaining to routinely performed temporal injection techniques, their expected esthetic outcomes as well as the intendant advantages, disadvantages, and procedure pearls. Подробнее

Journal of cosmetic dermatology

Platelet-rich plasma treatment for melasma: A pilot study.

Jun, 2020

Melasma treatments have varying success and are associated with some complications. Подробнее

Journal of cosmetic dermatology

A Validated Assessment Scale for Asian Chin Projection.

Aug, 2019

As the number of different aesthetic treatments increase, numerous photonumeric assessment scales have been developed and validated to measure the effectiveness of these new treatments and techniques. Photonumeric rating scales have been developed to objectively assess improvements in anatomical areas; however, these have been based on the features of Caucasian patients. Подробнее

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]

Validated Assessment Scales for the Female Asian Calf.

Aug, 2019

Clinical photonumeric scales have been developed and validated to objectively measure the effectiveness of aesthetic treatments in specific anatomical areas; however, these are based on the typical features of Caucasian patients. No clinical scale for Asian calf appearance currently exists. Подробнее

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]

Validation of a Photonumeric Assessment Scale for Grading the Slope of the Asian Forehead.

Aug, 2019

As the number of aesthetic treatments has grown, so have the number of photonumeric assessment scales used to compare the effectiveness of these aesthetic treatments in specific anatomical areas; however, these are primarily based on Caucasian features. Подробнее

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]

Severe vision loss caused by cosmetic filler augmentation: Case series with review of cause and therapy.

Oct, 2018

Hyaluronic acid (HA) injection is a popular nonsurgical, facial rejuvenating procedure. Due to the rapidly expanding use of HA injections, significant potential complications have also increased in frequency. Among these complications, the rare but most devastating one is arterial occlusion, which can result in skin necrosis or blindness. To describe the mechanisms behind vision loss secondary to hyaluronic acid injection and the efficacy of treatments to restore vision and associated ocular functionality. We reviewed six cases of patients from October 2011 to December 2017 who experienced vision loss after receiving facial HA injections and the subsequent treatments undertaken to attempt to reverse the vision loss and additional eye complications. Of the six patients, four received nose, one received forehead, and another one received temple injections. All six patients developed vision loss secondary to hyaluronic acid embolization in retinal or ophthalmic arteries. Additional complications included severe periorbital pain, ptosis, impairment of extraocular muscle functionality. Recovery of vision was dependent on the type, frequency, and duration of subsequent treatment. Vision loss is a rare but catastrophic complication caused by hyaluronic injection that occurs secondary to hyaluronic acid embolization in retinal or ophthalmic arteries due to retrograde flow from facial vascular anastomoses. We suggest the early supratrochlear/supraorbital hyaluronidase injection, ocular massage, and re-breathing into a plastic bag as safe, uncomplicated and effective methods to restore the retinal circulation and reverse vision loss. Подробнее

Journal of cosmetic dermatology

The layered anatomy of the jawline.

Aug, 2018

To investigate the layered anatomy of the jawline and to provide anatomic background for the formation of the labiomandibular sulcus, the jowl deformity, and the "double-chin" for safe and effective minimally invasive procedures. Подробнее

Journal of cosmetic dermatology

The posterior temporal supraSMAS minimally invasive lifting technique using soft-tissue fillers.

Aug, 2018

To investigate the effectiveness of the posterior temporal supraSMAS minimally invasive lifting technique and compared it to experiments performed in fresh human body donors by applying skin vector displacement measurement technology. Подробнее

Journal of cosmetic dermatology

The study of histological changes of the arterial vascular structure after hyaluronidase exposure.

Aug, 2018

Hyaluronic acid (HA) filler injection is commonly used for soft tissue augmentation. Uncommon but serious complication from filler injection is vascular occlusion. Hyaluronidase enzyme can be used to dissolve HA filler. Evidence demonstrates that hyaluronidase can penetrate through vessel wall after incubation. However, studies regarding effects of hyaluronidase on vessel wall after intraluminal injection are limited. The objective of this study is to evaluate histological changes of postmortem arteries after intravascular injection of hyaluronidase enzyme. Подробнее

Journal of cosmetic dermatology

Topography of the dorsal nasal artery and its clinical implications for augmentation of the dorsum of the nose.

Aug, 2018

Injections of filler into the nose for dorsum augmentation have a higher risk of complications due to the complicated blood supply and anastomotic channels in this area. Подробнее

Journal of cosmetic dermatology

A new long pulsed 940 nm diode laser used for hair removal in Asian skin types.

Jun, 2003

The theory of selective photothermolysis has led to the development of a variety of different hair removal laser systems.1,2 These lasers use follicular melanin as a target chromophore. At present the delivery of adequate fluences, optimizing wavelengths and pulse duration, and adequate epidermal cooling are the factors required to achieve effective hair removal. To further evaluate these factors a study was initiated to further investigate a new laser system. Подробнее

Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology

Current Practices in Hyaluronic Acid Dermal Filler Treatment in Asia Pacific and Practical Approaches to Achieving Safe and Natural-Looking Results.

2022

Complications such as delayed inflammatory reactions (DIRs) and unnatural outcomes can sometimes arise from hyaluronic acid (HA) dermal filler treatments and can be challenging to address. Given the popularity of HA dermal fillers for aesthetic procedures, there is a need for preventive strategies to minimize these complications. Two hundred practitioners from 10 regions in Asia Pacific who administer HA fillers completed a survey on prevention of DIRs and unnatural outcomes. Thirteen global experts convened to evaluate the current practices and propose practical approaches for safe and appropriate use of HA dermal fillers. From the survey, the top three measures used to reduce the risk of DIRs included choosing an appropriate HA filler, aseptic technique, and patient selection. Key strategies employed to achieve natural-looking outcomes were treatment customization, understanding the rheological properties and behavior of different HA fillers, and being conservative in treatment approach. The panel developed a concise reference guide aimed at minimizing the risk of DIRs while achieving natural aesthetic outcomes. Five practical considerations were recommended: patient assessment and individualization of treatment plan, choice of an appropriate HA filler, adequate knowledge of facial anatomy, strict adherence to aseptic methods, and proper injection technique. The panel highlighted the need for education efforts to increase awareness of differential immunogenicity between HA fillers and to improve understanding on the importance of preserving aesthetic individuality for optimal results. These practical insights from the global experts support practitioners in optimizing safety and quality of aesthetic treatment with HA fillers. Подробнее

Clinical, cosmetic and investigational dermatology

Delayed Inflammatory Reactions to Hyaluronic Acid Fillers: A Literature Review and Proposed Treatment Algorithm.

2020

There is a wide diversity of opinions regarding the management of delayed inflammatory reactions (DIRs) secondary to hyaluronic acid (HA)-based fillers. The plethora of approaches has led the authors to conduct a review regarding management and treatment of DIRs as well as establish therapeutic guidelines for this purpose. Подробнее

Clinical, cosmetic and investigational dermatology