Objectives: Prospective self-controlled study on comparison of low fluence Q-switched 1064-nm and conventional Q-Switched Picosecond/Nanosecond lasers in the treatment of café-au-lait macules

Objectives: To highlight the role of advanced cosmeceuticals—including growth factors, peptides, and antioxidants—in improving wound healing and reducing post-inflammatory hyperpigmentation (PIH) following laser procedures, particularly in Asian skin.

Introduction: Laser resurfacing procedures create controlled dermal injury to induce rejuvenation, but recovery is critical—especially for Asian skin, which has a higher propensity for PIH. Proper post-laser skincare can minimize complications, enhance healing, and improve patient satisfaction. This presentation examines the use of key cosmeceutical ingredients in each phase of wound healing.

Materials / method: A clinical review of studies evaluating the efficacy of L-ascorbic acid, EGF, bFGF, and signal peptides post-laser was conducted. Special attention was paid to trials involving split-face comparisons and data in Fitzpatrick III–V or Chinese populations. Recovery protocols were mapped according to the biological stages of healing: inflammation, proliferation, and remodeling.

Results: Vitamin C (L-AA) with ferulic acid reduced erythema and PIH when introduced 3–5 days post-laser.
Growth factors (EGF, bFGF) accelerated re-epithelialization and improved healing scores.
Peptides (GHK-Cu, palmitoyl peptides) enhanced texture and barrier function.
A phased topical strategy aligned with the wound healing timeline reduced recovery time and pigmentary side effects, particularly in Asian patients.

Conclusion: Optimizing recovery in laser-treated skin—especially for pigment-prone patients—requires active post-care. Clinical evidence supports the use of select cosmeceuticals to enhance healing and reduce complications. Dermatologists should implement phase-specific skincare protocols to support post-procedure outcomes and improve patient experience.

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