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Всемирный Конгресс 2019
Программа

ФОКУС НА S334

Видеозапись - Свободные лекции: анти-эйдж и космецевтики

Зал: Courtyard (Exhibition Hall - Level 2)
Дата: суббота 2 февраля 2019 в 15:00 до 16:00
Формат: ПУБЛИЧНЫЕ ВЫСТУПЛЕНИЯ > отдельный подиум в выставочной зоне для публичных выступлений, записанных профессиональной аудиовизуальной командой

Лекции сессии

Время	Спикеры	Заголовок сессии	Абстракт	Номер
15:00	Доктор Martin GODFREY	Effects of collagen bioactive peptides and natural antioxidants on proliferation and matrix protein: synthesis by cultured human dermal fibroblasts	Посмотреть	82243
15:15	Доктор Prasetyadi MAWARDI	Effectiveness of 1% caffeine gel in mild and moderate acne vulgaris therapy	Посмотреть	82259
15:30	Доктор Kerstin ORTLECHNER	Digital aging – Does the smartphone make us look old?	Посмотреть	82787
15:45	Доктор Jennifer PEARLMAN	The art and science of the perfect pout	Посмотреть	83079

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Старение

Филлеры: ГК (гиалуроновая кислота)

Анатомия

Стандарты красоты

Губы и рот (без хирургии)

Доктор Martin GODFREY

Доктор медицины

Великобритания

Другие авторы : Suzanne Edgar, Blake Hopley, Licia Genovese, Sara Sibilla, David Laight, Janis Shute

Effects of collagen bioactive peptides and natural antioxidants on proliferation and matrix protein: synthesis by cultured human dermal fibroblasts

Objectives: The aim of this in vitro study is to investigate the effects on normal human dermal fibroblast synthesis of collagen I and elastin, matrix metalloproteinases MMP-1 and MMP-3, and elastin degradation of collagen bioactive peptides, alone and in combination with other bioactive compounds found in collagen-based nutraceuticals, previously reported to increase skin elasticity in vivo.
Our hypothesis is that the antioxidant activity associated with the additives within these nutraceuticals interacts with the effects of the collagen peptides to enhance the stability of matrix proteins.

Introduction: Nutraceuticals containing collagen peptides, vitamins, minerals and antioxidants are innovative functional food supplements that have been clinically shown to have positive effects on skin hydration and elasticity in vivo.

Materials / method: In this in vitro study, we investigated the interactions between collagen peptides (0.3-8 kDa) and other constituents present in liquid collagen-based nutraceuticals on normal primary dermal fibroblast function in a novel, physiologically relevant, cell culture model crowded with macromolecular dextran sulphate.

Results: Collagen peptides significantly increased fibroblast elastin synthesis, while significantly inhibiting release of MMP-1 and MMP-3 and elastin degradation. The positive effects of the collagen peptides on these responses and on fibroblast proliferation were enhanced in the presence of the antioxidant constituents of the products.

Conclusion: These data provide a scientific, cell-based, rationale for the positive effects of these collagen-derived peptides and other nutraceutical compounds on skin properties, suggesting that enhanced formation of stable dermal fibroblast-derived extracellular matrices may follow their oral consumption.

Декларация COI

Получили ли вы финансовую поддержку для поисков этой ТЕМЫ?
Да
Укажите, пожалуйста, лица (индивидуальное, предприятие, организация): The research was funded by Minerva Research Labs

Были ли вам предоставлены гонорары, выплаты или иная компенсация за вашу работу в этом исследовании?
Да
Укажите лица (физическое лицо, предприятие, ассоциация): The research was funded by Minerva Research Labs

Есть ли у Вас финансовые отношения с лицами, тесно конкурирующими с препаратами, изделиями или приборами, указанными в вашей презентации?
Нет

Вы владеете или подали заявку на какие-либо патенты по инструментам, лекарствам или материалам для вашего исследования?
Да
Укажите дату....: European patents granted
и статус: 2013 and 2014

Эта работа представлена благодаря поддержке: Minerva Research Labs

Доктор Prasetyadi MAWARDI

Дерматолог

Индонезия

Другие авторы : Aris Cahyono, dermatolovenereologist

Effectiveness of 1% caffeine gel in mild and moderate acne vulgaris therapy

Objectives: This study was to determine the effectiveness of 1% caffeine gel in mild and moderate AV therapy.
Alternative therapy for acne vulgaris, relatively cheap, comfortable, many sources in Indonesia.

Introduction: Acne vulgaris is a chronic inflammatory skin disease that develops around the pilosebaceous apparatus and manifests as open and closed comedones as well as inflammatory papules, pustules, and nodules. The use of more than one medication due to multifactorial pathogenesis of the disease. This study was to determine the effectiveness of 1% caffeine gel in mild and moderate AV therapy.

Materials / method: This study was a double-blind randomized controlled trial. The study was conducted in February to April 2018, with 48 sample of AV patients who met the inclusion and exclusion criteria treated with caffeine 1% gel as a therapy group and tretinoin 0.025% cream as a control group, given for 6 weeks. Severity scoring using the Global Acne Grading Score (GAGS) and measuring the erythema index with mexameter® MX18. The results in both groups were analyzed using paired t test.

Results: The results of analysis for the GAGS of the treatment and control groups found that the 1% caffeine gel group caused a significant decrease in GAGS scores compared to the control group, especially at 4th and 6th weeks of measurement (p <0.05). Erythema index in the 1% caffeine gel group showed significantly better results than controls on the forehead and chin area (p <0.05).

Conclusion: 1% caffeine gel had a significant therapeutic effect compared to controls in mild and moderate AV therapy, which were assessed through changes in GAGS and erythema index.

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Нет

Эта работа не была поддержана никаким прямым или не прямым финансированием. Находится под собственной ответственностью автора.

Доктор Kerstin ORTLECHNER

Дерматолог

Австрия

Другие авторы : Dr. Kerstin Ortlechner

Digital aging – Does the smartphone make us look old?

Objectives: 1. Facts and pearls about Digital Aging
2. Broaden one`s mind about HEV light
3. Manage the prophylaxe and protection against blue light with diverse treatments involving antioxidants, scattering agents and screens

Introduction: We all know that staring at screens for hours on end is damaging to our eyesight, can ruin our sleep patterns and can shorten our concentration spans. But there has been a recent discovery that may make even the most ardent selfie-taker throw their phone in the sea – all of that blue light from our smartphones, tablets and laptop screens could potentially be making us look older. Yes, we can now add Screen Face to the list of ailments allegedly caused by our dependence on digital technology – along with Text Neck and Cellphone Elbow.

Materials / method: Given the abundance of data available on the negative effects of ultraviolet light on the skin, we are starting to focus our attention on damage caused by other forms of light, such as HEV light (high energy visible light – otherwise known as blue light) and the prophylaxe/ protection against.

Results: The purported culprit of digital aging is the HEV emitted by our devices. High-energy visible light refers to the higher-frequency, shorter wavelengths of light in the violet-blue band of the visible spectrum. HEV is present in daylight, but it is also emitted by fluorescent lighting and LEDs. The blue light penetrates skin more deeply than UVA or UVB rays, and in doing so releases free radicals, which lead to pigmentation disorders and a decrease in collagen. Ultimately, a slowdown in collagen production results in a loss of volume in the face, which is a telltale sign of aging.

Conclusion: HEV is soon likely to become as much of a buzzword in the world of aesthetic medicine as SPF was at the start of the 1990s. Similarities can be drawn from this example when considering the fact that there was also little known about UVA and UVB during this time. When contemplating the potential repurcussions, it is safe to say that it is definetely going to become a mainstream skin-care movement. In addition to rampant smartphone usage, the trend seems to be a byproduct of modern times.

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Доктор Jennifer PEARLMAN

Доктор медицины

Канада

Другие авторы : Dr. Jennifer Pearlman

The art and science of the perfect pout

Objectives: **Discuss the Standards of Beauty relating to the Lip/Perioral region and Age related changes
**Present a 7x7-step approach to a personalized assessment of the Lip/Perioral region
**Differentiate between Enhancement (i.e. symmetry, volume, shape, internal/external proportion) v. Rejuvenation (i.e. age related changes)
**Provide best practice and advanced techniques to enhance and rejuvenate the Lip/Perioral region

Introduction: The lip is a focal point of the face and plays a vital role in expressing beauty, youth and sexuality. The beauty standard is evolving due to changing global, cultural and social influences. Predictable age related changes occur in this region and are readily addressed by non-surgical cosmetic treatment. A higher degree of aesthetic expertise is required in this delicate region that combines a personalized assessment of needs and goals and an approach that differentiates enhancement from rejuvenation. A 7x7 approach to the lip/perioral region can allow masterful beautification.

Materials / method: The presentation will include visual images, diagrams, measurements, and before/after images to provide a roadmap to assess and treat the lip and perioral region. The current global beauty standard will be presented. Age related changes will be reviewed. a 7 feature assessment plan will be described evaluating; commissures, cupid's bow, tuburcles, pout, vermillion border, philltrim column and ptosis. A 7-step treatment plan will be reviewed considering; shape, symmetry, volume, internal proportion, external proportion, corners, and texture. Enhancement will be differentiated from rejuvenation.

Results: Expert aesthetic technique and a comprehensive approach are required to masterfully treat the lip/perioral region. The 7-feature assessment of the regional anatomy and a treatment plan that considers 7-aspects of the beauty standard can help improve outcomes. Aging of the lip/perioral region is predictable and easily addressed by non-surgical treatments including dermal fillers and cosmetic technology. Differentiating enhancement from rejuvenation goals is key to individualize results and ensure that outcomes respect beauty standards as well as the personal needs and goals of each patient.

Conclusion: The lip requires a high degree of aesthetic expertise and a detailed, personalized assessment of the patients needs and goals. A 7x7 approach of the region can guide a masterful non-surgical treatment to enhance and rejuvenate the lip and perioral region using injectable dermal fillers. Masterful injection technique can deliver results that exceed patient expectations.

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Всемирный Конгресс 2019 Программа

ФОКУС НА S334

Видеозапись - Свободные лекции: анти-эйдж и космецевтики

Лекции сессии

Рекомендуемые сессии

Всемирный Конгресс 2019
Программа