摘要

Objectives: 1. Understand changes occurring in the aging skin 2. Formulate a comprehensive treatment to address the different elements of the aging skin using laser and light 2. Learn a combination treatment approach of laser and light in treatment and understand its efficacy and safety Introduction: The aging process involves laxity, hyperpigmentation, and telangiectasias. It is important to target those elements of aging to be successful at achieving rejuvenation. Our goal is to determine the efficacy, safety, and patient satisfaction of a combination IPL and 1440nm diode laser versus either treatment alone. Materials / method: 40 subjects were enrolled in this randomized split-face trial. 20 were randomized to group A (received IPL on one side of the face and IPL followed by the 1440nm diode laser on the other side), and 20 were randomized to group B (received 1440nm diode laser on one side of the face and IPL followed by the 1440nm diode laser on the other side). Results: Investigators reported a percent improvement of 40%-50% in all three groups at day 120; blinded investigator Global Aesthetic Improvement Scores were better in the combination group- 90% compared to 84% and 83% in the IPL and 1440nm diode laser groups, respectively. Wrinkling scores was significantly improved in the 1440nm diode and combination groups. Hyperpigmentation and telangiectasias were significantly improved in all three groups. Adverse events were self-limited. Conclusion: Combination treatment with IPL and 1440nm diode laser was found to be safe and effective and resulted in higher subject satisfaction.