Objectives: Understanding the various minimal invasive treatment modalities of androgentic alopecia and the role peptides may play in the future for this indication
Introduction: Androgentic alopecia (AA) is one of the most important cosmetic indications in man. The current therapies all have limitations. Some, e.g. finasteride, may have severe side-effects, others only have minor efficacy. One of the new treatment options in AA are injections with peptides. This therapy named 'hair fillers' has recently been introduced and may pose a new era in the treatment of AA
Materials / method: Hair growth is a complex process, but in recent years it has become much clearer how the pathophysiology of AA comes about. From this, the potential targets for therapy are also identified.
Results: The process of identifying peptides for various cosmetic applications is rapidly unfolding, also for alopecia. Each peptide identified targets a different area in the pathophysiology. A mix of these peptides is now used for injection therapy
Conclusion: Injections with a mix of peptides can provide a new therapy for AA, although much has to be studied before the the definite place of hair fillers in the armamentarium of AA can be fully assessed
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