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Objectives: Not only the contours and youthfulness of the face, but also of the neck, décolleté and hands have a surprisingly important effect on the overall appearance. When evaluating the aging of this areas, a few characteristics must be taken into consideration: laxity of the skin, volume loss and pigment alterations.

As many factors contribute to the aging of this areas, a comprehensive approach is essential for its rejuvenation. In hands nonsurgical rejuvenation nowadays, treatment with hyaluronic acid (HA) has become the standard regimen.

Introduction: The aim of this study is to analyze two different cases in female subjects for hands rejuvenation. The proposed protocol includes hyaluronic acid fillers and hyaluronic acid stable hybrid cooperative complexes (HA-HCC).

Materials / method: The treatment performed was done with canula 25G 38mm on the dorsal superficial lamina with fanning technique, a total of 1,5mL of HA-HCC per hand was injected per treatment session, 2 doses of HA-HCC were injected at day 0 and day 30. One month later a touch up was done with HA filler on the hands 1mL per hand was injected.

Results: Results show a visibly smoother skin, improved texture and barely any lines left, also it is observed a clear improvement of the volume without any contour irregularities or tissue bulking.

Conclusion: Combination treatments are a quick and generally safe option, the results will not be permanent and the effects will last for around 12 months. It is wise to advise the patient to have a top-up session every six to eight months in order to achieve continuous results. It is also important to make patients aware that a younger looking skin will help to give a more harmonious rejuvenation.

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