Objectives: We were interested in the use of Botulinum toxin in the modification of the smile.  
The muscular anatomy of the region is complex and intricate.
 By a good knowledge of this anatomy and an understanding of the muscular balance we managed  influencing the smile in dynamics; our ambition is now focused on modifying the position of the commissures in static. This is a more  ambitious and more delicate goal, which even when effective is not necessarily perceived as positive by the patients.
The management of the smile by the Botulinum Toxin is not without risks, we will give you technical precautions to avoid complications.

利益冲突声明

您有否接受任何资金来支持研究这个主题？
否

您是否接受过关于这项研究的任何酬金或其他报酬？
否

你是否和任何与您的研究所涉及的药物，材料或工具有密切联系的实体存在财务关系？
否

你是否拥有或者您已经为您此研究中的工具，药物或材料申请任何专利？
否

这项工作没有任何直接或间接的资金支持。由作者自己承担责任。

利益冲突声明

您有否接受任何资金来支持研究这个主题？
否

您是否接受过关于这项研究的任何酬金或其他报酬？
否

你是否和任何与您的研究所涉及的药物，材料或工具有密切联系的实体存在财务关系？
否

你是否拥有或者您已经为您此研究中的工具，药物或材料申请任何专利？
否

这项工作没有任何直接或间接的资金支持。由作者自己承担责任。

Objectives: Upper face toxin injection is a very common aesthetic procedure in the world. The Asians have less wrinkles over upper face compare with Caucasians. The usual dose for periorbital wrinkles in Asian is much less than Caucasian. In some condition, the same dose of toxin periorbital should be considered in Asian patients.

Introduction: According to the ASAPS annual statistic review, neurotoxin has been the most popular cosmetic procedure worldwide for over 20 years. Neurotoxins have dozens of applicable indications across many disciplines, and this list is expanding every year.

Materials / method: One of the on-label uses of neurotoxin is the treatment of crow’s feet, which was approved by the US FDA in 2015, with a suggested dose of 12 units per side.

Results: In multiple articles, however, this dosage was adjusted to a lower level in Asian patients, for two main reasons. First, to prevent a frozen-looking appearance, and second, to account for anatomical structural differences between Caucasians and Asians.

Conclusion: In this talk, I will present the clinical result of different doses for crow’s feet treatment with neurotoxin in Asian patients.

利益冲突声明

您有否接受任何资金来支持研究这个主题？
否

您是否接受过关于这项研究的任何酬金或其他报酬？
否

你是否和任何与您的研究所涉及的药物，材料或工具有密切联系的实体存在财务关系？
否

你是否拥有或者您已经为您此研究中的工具，药物或材料申请任何专利？
否

这项工作没有任何直接或间接的资金支持。由作者自己承担责任。