Objectives: Delegates attending this lecture will gain an understanding of the pathophysiology of cellulite and its link to iron toxicity, vascular dysfunction, and chronic inflammation. The session will demonstrate Alidya’s unique formula and its scientifically proven components—EDTA, amino acids, mannitol, bicarbonate, calcium ascorbate, and alpha-glucopyranose—and how they work synergistically to restore skin health, improve microcirculation, and visibly reduce cellulite. Practical insights into its application and clinical outcomes will be shared
Introduction: Cellulite affects 90% of post-pubertal women, characterized by skin dimpling and structural irregularities due to chronic inflammation, iron deposition, and ECM imbalance. Prof. Pasquale Motolese’s research identified iron toxicity as a critical factor in cellulite development, and this key finding was the basis for the development of Alidya. This medical device targets these underlying causes through chelation, detoxification, and tissue regeneration, offering a novel approach to this stubborn aesthetic problem..
Materials / method: The presentation will summarize clinical and histological data, including biopsies analysed using PERLS staining, which confirmed iron and hemosiderin deposits in cellulite-affected tissues. Results from recent multicenter studies using thermography, HD ultrasound, and body measurements will highlight the efficacy of Alidya in reducing oedema, improving skin texture, and restoring ECM balance. Application protocols and patient outcomes will also be discussed.
Conclusion: Alidya represents a ground-breaking injectable therapy targeting the root causes of cellulite. By addressing iron toxicity, oxidative stress, and chronic inflammation, it restores tissue physiology, enhances collagen production, and reduces visible irregularities. Clinical evidence supports its efficacy, demonstrating smoother, healthier skin and improved patient satisfaction. After more than 10 years in the aesthetic market, this innovative solution provides a scientifically backed approach to managing cellulite
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