Objectives: The problematic of the planning of the clinical interventions impacting health behaviors in older age.
Timing of death as a controllable event as a new cultural phenomenon.
Preventive clinical interventions and their link to self-promotion of longevity,
Role of technological proficiencies.
Emergence of new forms of subjectivity.

Introduction: Infectious diseases, cardiovascular disorders and cancer are real health issues, but none of them is foreseen as the major cause of death in ten years form now. The major threat in our society has become premature death due to overdosage of legal antalgics such as codeine, which are regularly prescribed and increasingly consumed. Besides, the greatest stress is represented by life expectancy itself.

Materials / method: The mechanisms of sustained stress have largely been investigated. The imbalance of the parasympathetic/ortosympathetic system, seems related to the deleterious effect of elevated cortisolemia. «Leaky gut syndrome» and its looming companion «sickness syndrome» with loss of interest, difficulty to concentrate, memory lapses, insomnia, chronic fatigue syndrome, obsessional thoughts, social isolation, depression, anxiety, obsessional neurosis. Of course all if these ailments concur to search for some form of relief, ultimately leading to addiction.

Results: The development of interactive tools (such as the nutritional survey platform of the RISTOMED study ) address elderly people, with limited income, poor diet and restricted social interactions as a sensitive target. Growing concern to improve quality of life in the context of increased life expectancy could be benefit from nutraceutic-mediated mood improvement,

Conclusion: In summary, it seems that in order to break the malignant circle of aging-stress-addiction, new digital tools could pave the way towards prevention and a better management of stressful episodes associated to increased life expectancy. Together with an optimized management of mucosal immunity breaking the deleterious effects of the sneaking leaky gut, a welcome reduction of life-threatening behaviours would be obtained.

d’Alessio PA Salutogenesis and beyond. Dermatologic Therapy 2018 ;e12783. https://doi.org/10.1111/dth.12783.

Disclosures

Did you receive any funding to support your research for this TOPIC?
Yes
Please specify entities (individual, company, society): EC FP7 RISTOMED Capacities study n°222230

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability

Objectives: Describe the new paradigm of age prevention

Introduction: Currently, age prophylaxis and skin health can be achieved with a plethora of non-invasive cosmetic procedure, including laser, ultrasound, radiofrequency energy-devices, toxins, fillers, topicals and internal biologics. Together, and via a strategic combination customized to the patient’s needs and anatomic nuances, the signs and processes of aging can be forestalled and even reversed, all by capturing a successful aesthetic outcome.

Materials / method: Key components of a successful anti-aging strategy include: protection with antioxidants/sunscreens, promotion of epidermal turnover with chemical peels, laser ablation and dermabrasion, collagen/elastin remodeling with energy-based modalities and volume repletion with volumetric (PLLA, PMMA, CaHa) and dermal (HA) fillers. For volume repletion, a trivector bimodal methodology is critical in order to successfully replace loss of both deep and superficial fat pads, bone and muscle.

Results: Replacing the deep fat pads requires supraperiosteal injections that can re-create a structural platform of the upper, middle and lower face. To maximize patient comfort, three injection access points are utilized, known as trivector points: one at the temporal fossa, one at the midface and one at the jawline.Following the reinforcement of the deep anatomical areas, deep dermal/subcutaneous injections are done to customize the treatment according to anatomic facial parameters and individual preferences.

Conclusion: This bimodal, trivector approach using new generation volumetric and dermal fillers, with intrinsic regenerating biological properties can serve as a prophylactic approach to aging and securing of skin health.

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability