MD (Milan) PhD (Utrecht) Hematologist , Hemorheologist, Cell biologist. Fields of expertise : cell senescence, inflammation, reversible senescence, anti-inflammatory strategies, anti-aging strategies. Link between stress and chronic inflammatory diseases, implication of microbiota and barrier function of the gut.
Tissue repair, elasticity, reversibility of the senscent phenotype.
Professor of cell biology (1992-2012) at medical faculties Paris 5 (René Descartes) and Paris Sud-11 Universities created AISA Therapeutics in 2005 (3 patents granted in EU, US, China) following the national award for innovative research to promote IP, R&D and commercialisation of a bioactive complex able to stop inflammation in senescent cells, reverse senescence, treat wounds and scars. Chronix inflammatory and degenerative diseases and their dependence on stress. Analysis of lifestyle influence on well-being. New book : “Inflammation-body alert system” Dangles ed., April 2019.
Impact of diet and nutraceutical supplementation on inflammation in elderly people. Results from the RISTOMED study, an open-label randomized control trial. Ostan R, Béné MC, ... Brigidi P, d’Alessio PA. Clin Nutr. 2016;35:812-818.
AISA can control the inflammatory facet of SASP. d’Alessio PA, Béné MC, Mechanisms of Ageing and Development, in press, 2020.