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Dr Jonathan ROOS

Oculoplastic Surgeon
United Kingdom
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Jonathan ROOS's publications (11)

Update on the clinical assessment and management of thyroid eye disease.

Sep, 2019

To offer an update on advances and controversies in the assessment, investigation and treatment of thyroid eye disease (TED), a disfiguring orbital autoimmune disease, which can manifest with diplopia and threaten not only sight - but also life. read more

Current opinion in ophthalmology

Periocular hyaluronic acid fillers: applications, implications, complications.

Sep, 2019

The use of dermal filler in the periocular area is increasing - both for functional and aesthetic indications. Hyaluronic acid fillers dominate the market; these treatments offer an alternative to some surgical procedures with the advantage of instant results, minimal healing time and low complication rates. However, success depends on judicious selection of patients, products and procedures to achieve favourable outcomes. This article reviews current understanding of the principal complications in the periocular area and their management. read more

Current opinion in ophthalmology

Sirolimus (rapamycin) for the targeted treatment of the fibrotic sequelae of Graves' orbitopathy.

04, 2019

Rapamycin (alternatively known as sirolimus) is a macrolide immunosuppressant commonly used for organ transplantation. It acts both on lymphocytes through the mechanistic target of rapamycin (mTOR) pathway to reduce their sensitivity to interleukin-2 (IL-2) and, importantly, also has anti-fibrotic properties by acting on myofibroblasts. The latter have been implicated in the pathogenesis of thyroid eye disease (TED). read more

Eye (London, England)
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Jonathan ROOS's scientific societies (1)