Epidemiological studies show a positive relationship between physical activity and cartilage volume, suggesting that exercise may protect against osteoarthritis. Cross-sectional experimental studies, however, have failed to show significant differences in knee cartilage morphology between athletes and nonathletic controls. The aim of the study was to test the hypothesis that knee cartilage morphology, specifically regional cartilage thickness and global subchondral bone area, is modified in sedentary, untrained adult women who increased their physical fitness during a 3-month supervised exercise intervention. read more

Cells, tissues, organs

The Anatomy of the Aging Face: A Review.

Jun, 2016

Rejuvenative procedures of the face are increasing in numbers, and a plethora of different therapeutic options are available today. Every procedure should aim for the patient's safety first and then for natural and long-lasting results. The face is one of the most complex regions in the human body and research continuously reveals new insights into the complex interplay of the different participating structures. Bone, ligaments, muscles, fat, and skin are the key players in the layered arrangement of the face.Aging occurs in all involved facial structures but the onset and the speed of age-related changes differ between each specific structure, between each individual, and between different ethnic groups. Therefore, knowledge of age-related anatomy is crucial for a physician's work when trying to restore a youthful face.This review focuses on the current understanding of the anatomy of the human face and tries to elucidate the morphological changes during aging of bone, ligaments, muscles, and fat, and their role in rejuvenative procedures. read more

Facial plastic surgery : FPS

Comparison of radiographic joint space width and magnetic resonance imaging for prediction of knee replacement: A longitudinal case-control study from the Osteoarthritis Initiative.

Jun, 2016

To evaluate whether change in fixed-location measures of radiographic joint space width (JSW) and cartilage thickness by MRI predict knee replacement. read more

European radiology Load more

Sebastian COTOFANA's connections (61)

Dr Francesco BARBAGALLO

Dr Dimitrios PANOURGIAS

Plastic Surgeon

Greece

Dr Natallia ROMANOWSKA

+ 54 Connections

Sebastian COTOFANA's main interests

Injectables

Face surgery

Pr Sebastian COTOFANA

Sebastian COTOFANA's schedule

IMCAS World Congress 2020

Cadaver workshop: superficial echographic facial anatomy

Galderma Symposium - Empowering personalization through the decades

Galderma Symposium

Updates of toxins in functional anatomy

Body shaping & body tightening (in collaboration with 5CC)

Rheological and biophysical properties of fillers

Sinclair Symposium - Bespoke aesthetic treatment: Sinclair’s new approach

Sebastian COTOFANA's lectures (36)

Sebastian COTOFANA's publications (30)

Effects of exercise intervention on knee morphology in middle-aged women: a longitudinal analysis using magnetic resonance imaging.

The Anatomy of the Aging Face: A Review.

Comparison of radiographic joint space width and magnetic resonance imaging for prediction of knee replacement: A longitudinal case-control study from the Osteoarthritis Initiative.

Reference data on muscle volumes of healthy human pelvis and lower extremity muscles: an in vivo magnetic resonance imaging feasibility study.

Midface: Clinical Anatomy and Regional Approaches with Injectable Fillers.

Upper Face: Clinical Anatomy and Regional Approaches with Injectable Fillers.

Greater Lateral Femorotibial Cartilage Loss in Osteoarthritis Initiative Participants With Incident Total Knee Arthroplasty: A Prospective Cohort Study.

Is Pain in One Knee Associated with Isometric Muscle Strength in the Contralateral Limb?: Data From the Osteoarthritis Initiative.

Influence of defect size and localization on the engagement of reverse Hill-Sachs lesions.

Contralateral knee effect on self-reported knee-specific function and global functional assessment: data from the Osteoarthritis Initiative.

The arterial blood supply of the helical rim and the earlobe-based advancement flap (ELBAF): a new strategy for reconstructions of helical rim defects.

Redefining the vascular anatomy of the peroneus brevis muscle flap.

Is loss in femorotibial cartilage thickness related to severity of contra-lateral radiographic knee osteoarthritis?--longitudinal data from the Osteoarthritis Initiative.

Thigh muscle cross-sectional areas and strength in knees with early vs knees without radiographic knee osteoarthritis: a between-knee, within-person comparison.

Trajectory of cartilage loss within 4 years of knee replacement--a nested case-control study from the osteoarthritis initiative.

Longitudinal change in femorotibial cartilage thickness and subchondral bone plate area in male and female adolescent vs. mature athletes.

Longitudinal (one-year) change in cartilage thickness in knees with early knee osteoarthritis: A within-person between-knee comparison.

Sustained clinical and structural benefit after joint distraction in the treatment of severe knee osteoarthritis.

Relationship between knee pain and the presence, location, size and phenotype of femorotibial denuded areas of subchondral bone as visualized by MRI.

Quantitative MRI measures of cartilage predict knee replacement: a case-control study from the Osteoarthritis Initiative.

Cartilage thickening in early radiographic knee osteoarthritis: a within-person, between-knee comparison.

Mechanisms of proximal hamstring rupture in a non-athlete healthy middle-aged female.

Hand joint space narrowing and osteophytes are associated with magnetic resonance imaging-defined knee cartilage thickness and radiographic knee osteoarthritis: data from the Osteoarthritis Initiative.

Tissue structure modification in knee osteoarthritis by use of joint distraction: an open 1-year pilot study.

Greater rates of cartilage loss in painful knees than in pain-free knees after adjustment for radiographic disease stage: data from the osteoarthritis initiative.

In vivo measures of cartilage deformation: patterns in healthy and osteoarthritic female knees using 3T MR imaging.

Correlation between single-slice muscle anatomical cross-sectional area and muscle volume in thigh extensors, flexors and adductors of perimenopausal women.

Presence, location, type and size of denuded areas of subchondral bone in the knee as a function of radiographic stage of OA - data from the OA initiative.

NOD2/CARD15 genotype influences MDP-induced cytokine release and basal IL-12p40 levels in primary isolated peripheral blood monocytes.

The 14-bp deletion polymorphism in the HLA-G gene displays significant differences between ulcerative colitis and Crohn's disease and is associated with ileocecal resection in Crohn's disease.

Sebastian COTOFANA's connections (61)

Sebastian COTOFANA's main interests