Objectives: Prospective self-controlled study on comparison of low fluence Q-switched 1064-nm and conventional Q-Switched Picosecond/Nanosecond lasers in the treatment of café-au-lait macules

Objectives: To highlight the role of advanced cosmeceuticals—including growth factors, peptides, and antioxidants—in improving wound healing and reducing post-inflammatory hyperpigmentation (PIH) following laser procedures, particularly in Asian skin.

Introduction: Laser resurfacing procedures create controlled dermal injury to induce rejuvenation, but recovery is critical—especially for Asian skin, which has a higher propensity for PIH. Proper post-laser skincare can minimize complications, enhance healing, and improve patient satisfaction. This presentation examines the use of key cosmeceutical ingredients in each phase of wound healing.

Materials / method: A clinical review of studies evaluating the efficacy of L-ascorbic acid, EGF, bFGF, and signal peptides post-laser was conducted. Special attention was paid to trials involving split-face comparisons and data in Fitzpatrick III–V or Chinese populations. Recovery protocols were mapped according to the biological stages of healing: inflammation, proliferation, and remodeling.

Results: Vitamin C (L-AA) with ferulic acid reduced erythema and PIH when introduced 3–5 days post-laser.
Growth factors (EGF, bFGF) accelerated re-epithelialization and improved healing scores.
Peptides (GHK-Cu, palmitoyl peptides) enhanced texture and barrier function.
A phased topical strategy aligned with the wound healing timeline reduced recovery time and pigmentary side effects, particularly in Asian patients.

Conclusion: Optimizing recovery in laser-treated skin—especially for pigment-prone patients—requires active post-care. Clinical evidence supports the use of select cosmeceuticals to enhance healing and reduce complications. Dermatologists should implement phase-specific skincare protocols to support post-procedure outcomes and improve patient experience.

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability