Objectives: Facial pores are the result of high sebum excretion, decreased elasticity
around pores, and increased hair follicle volume. Conventional treatment options such as topical retinoids, chemical peels, oral anti-androgens, and laser devices have shown mixed results, especially when treating large pores. In this study, the use of exosomes and Botulinum Toxin type A (BTXA) was explored to treat large facial pores.
Materials / method: Subjects with large facial pores were selected for this study and treated in the following sequence. On day 1, the subjects were treated using air dissection and micro-droplet Botulinum Toxin type A. After one week, the exosome was applied to the treatment area using a meso roller. Two weeks later, another round of air dissection and micro-droplet BTXA injection was followed by the exosome application the following week. The subjects were followed up 3 weeks and 6 weeks after day 1 to assess the pore size, depth, and skin roughness using QuantifiCare 3D Lifeviz.
Results: Improvements in pore size and depth, especially for small and medium-sized
pores were recorded during the first follow-up on week 3. After 6 weeks, significant
improvements to pore size and depth were recorded, including large pores. Assessment using QuantifiCare 3D Lifeviz showed improvements in the subject’s skin roughness throughout the follow-up sessions.
Conclusion: Conventional treatments for facial pores have shown mixed results when
used for the treatment of large facial pores. In this study, the use of exosomes and
Botulinum Toxin type A has been demonstrated to be effective in the treatment of large facial pores.
Disclosures
Did you receive any funding to support your research for this TOPIC?
No
Were you provided with any honoraria, payment or other compensation for your work on this study?
No
Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No
Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No
This work was not supported by any direct or non direct funding. It is under the author's own responsability